Publication Name	World Journal of Gastroenterology
Manuscript ID	1516
Country	China

Received	2012-12-17 17:21
Peer-Review Started	2012-12-17 20:44
To Make the First Decision	2013-02-01 21:48
Return for Revision	2013-02-17 10:24
Revised	2013-03-01 14:46
Second Decision	2013-03-22 12:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-03-23 09:21
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-04-18 23:11
Typeset the Manuscript	2013-05-07 19:45
Publish the Manuscript Online	2013-05-14 16:05

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Prognostic value of preoperative mean corpuscular volume in esophageal squamous cell carcinoma
Manuscript Source	Invited Manuscript
All Author List	Yu-Zhen Zheng, Shu-Qin Dai, Wei Li, Xun Cao, Yong Li, Lan-Jun Zhang, Jian-Hua Fu and Jun-Ye Wang
Funding Agency and Grant Number
Corresponding Author	Jun-Ye Wang, Professor, Department of Thoracic Oncology, Cancer Center, Sun Yat-Sen University, No. 651, Dongfeng Road East, Guangzhou 510060, Guangdong Province, China. zhengyzh@sysucc.org.cn
Key Words	Preoperative markers; Mean corpuscular volume; Prognosis; Resectable; Esophageal neoplasms
Core Tip	Elevated mean corpuscular volume (MCV) has been shown to predict the risk of esophageal squamous cell carcinoma (ESCC). We hypothesized that pretreatment MCV could predict prognosis. In analyzing 298 patients with ESCC, we found that the optimal cut-off for preoperative MCV was 95.6 fl. Multivariate analysis showed that high (> 95.6 fl) preoperative MCV was a negative prognostic factor, along with advanced stage, upper thoracic location and lower preoperative albumin, in patients with ESCC. Median overall survival was significantly longer in patients with low (≤ 95.6 fl) than high preoperative MCV (27.5 mo vs 19.5 mo, P < 0.001).
Publish Date	2013-05-14 16:05
Citation	Zheng YZ, Dai SQ, Li W, Cao X, Li Y, Zhang LJ, Fu JH, Wang JY. Prognostic value of preoperative mean corpuscular volume in esophageal squamous cell carcinoma. World J Gastroenterol 2013; 19(18): 2811-2817
URL	http://www.wjgnet.com/1007-9327/full/v19/i18/2811.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i18.2811

Full Article (PDF)	WJG-19-2811.pdf
Manuscript File	1516-Review.doc
Answering Reviewers	1516-Answering reviewers.doc
Copyright License Agreement	1516-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	1516-Language certificate.pdf
Peer-review Report	1516-Peer review(s).pdf
Scientific Editor Work List	1516-Scientific editor work list.doc