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Publication Name World Journal of Gastroenterology
Manuscript ID 1540
Country China
Received
2012-12-18 21:07
Peer-Review Started
2012-12-19 14:53
To Make the First Decision
2012-12-27 12:21
Return for Revision
2012-12-28 09:21
Revised
2013-01-01 14:56
Second Decision
2013-02-06 11:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-02-06 12:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-03-27 09:10
Publish the Manuscript Online
2013-04-09 16:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Autobiography
Article Title Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer
Manuscript Source Invited Manuscript
All Author List Jie Chen, Su-Jun Zhou, Yun Zhang, Guo-Qiang Zhang, Tian-Zhou Zha, Yi-Zhong Feng and Kai Zhang
Funding Agency and Grant Number
Corresponding Author Kai Zhang, MD, Department of General Surgery, Yixing People's Hospital, the Affiliated Hospital of Jiangsu University, No. 75, Tongzhen Guan Road, Yixing 214200, Jiangsu Province, China. yxphpwk@163.com
Key Words Galectin-1; Vascular endothelial growth factor; Gastric cancer; Prognosis
Core Tip Galectin-1 and vascular endothelial growth factor (VEGF) played important roles in angiogenesis and progression of malignant tumor, while their expression in Chinese gastric cancer and relationship between the two parameters and clinicopathological features, as well as prognostic value remained largely unknown. In this present study, we examined 214 gastric cancer samples for the presence of galectin-1 oncoprotein and VEGF by immunohistochemistry and found that overexpressions of galectin-1 and VEGF were related with tumor progression and poor survival, and our findings supported an association between galectin-1 and VEGF expression. These two molecules may serve as independent predicative markers for patient prognosis in gastric cancer.
Publish Date 2013-04-09 16:03
Citation Chen J, Zhou SJ, Zhang Y, Zhang GQ, Zha TZ, Feng YZ, Zhang K. Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer. World J Gastroenterol 2013; 19(13): 2073-2079
URL http://www.wjgnet.com/1007-9327/full/v19/i13/2073.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i13.2073
Full Article (PDF) WJG-19-2073.pdf
Manuscript File 1540-Review.doc
Answering Reviewers 1540-Answering reviewers.doc
Copyright License Agreement 1540-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate 1540-Language certificate.pdf
Peer-review Report 1540-Peer review(s).docx
Scientific Editor Work List 1540-Scientific editor work list.doc