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Articles Published Processes
6/20/2015 5:38:00 PM | Browse: 881 | Download: 1285
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Received |
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2014-12-06 20:31 |
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Peer-Review Started |
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2014-12-08 10:47 |
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To Make the First Decision |
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2015-01-22 16:48 |
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Return for Revision |
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2015-01-27 16:30 |
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Revised |
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2015-02-06 11:58 |
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Second Decision |
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2015-03-11 15:33 |
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Accepted by Journal Editor-in-Chief |
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2015-03-12 02:42 |
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Accepted by Company Editor-in-Chief |
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2015-03-19 17:28 |
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Articles in Press |
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2015-03-19 17:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-03-26 14:12 |
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Typeset the Manuscript |
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2015-06-02 18:16 |
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Publish the Manuscript Online |
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2015-06-20 17:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Study |
| Article Title |
High level of intercellular adhesion molecule-1 affects prognosis of patients with hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Peng-Peng Zhu, Sheng-Guang Yuan, Yan Liao, Li-Ling Qin and Wei-Jia Liao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81260328 |
| National Natural Science Foundation of China |
81372163 |
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| Corresponding Author |
Dr. Wei-Jia Liao, Affiliated Hospital of Guilin Medical University, Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair, No. 15 Lequn Road, Xiufeng District, Guilin 541001, Guangxi Zhuang Autonomous Region, China. liao288@163.com |
| Key Words |
Hepatocellular carcinoma; Intercellular adhesion molecule-1; Prognosis; Biomarker; Metastasis |
| Core Tip |
Our previous research and other studies found that intercellular adhesion molecule-1 (ICAM-1) is overexpressed in hepatocellular carcinoma (HCC) and might be a biomarker for HCC diagnosis. However, the correlation between ICAM-1 and clinicopathologic features and its prognostic significance for HCC have not been explored. In this paper, we validate that ICAM-1 promotes HCC metastasis and that high serum ICAM-1 is significantly associated with alpha-fetoprotein, clinical tumor-node-metastasis stage, portal vein tumor thrombus, distant metastasis, recurrence, disease-free survival and overall survival. ICAM-1 may be a promising serological biomarker for HCC diagnosis and prognosis and may provide a useful reference for the prediction of intra- and extrahepatic metastasis. |
| Publish Date |
2015-06-20 17:38 |
| Citation |
Zhu PP, Yuan SG, Liao Y, Qin LL, Liao WJ. High level of intercellular adhesion molecule-1 affects prognosis of patients with hepatocellular carcinoma. World J Gastroenterol 2015; 21(23): 7254-7263 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i23/7254.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i23.7254 |
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