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Publication Name World Journal of Gastroenterology
Manuscript ID 1597
Country/Territory China
2012-12-21 23:13
Peer-Review Started
2012-12-22 16:02
To Make the First Decision
2013-03-18 15:22
Return for Revision
2013-03-19 20:55
2013-03-22 22:20
Second Decision
2013-05-09 14:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-10 06:44
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-06-07 09:26
Publish the Manuscript Online
2013-06-14 23:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Autobiography
Article Title Combination treatment with comprehensive cryoablation and immunotherapy in metastatic hepatocellular cancer
Manuscript Source Invited Manuscript
All Author List Li-Zhi Niu, Jia-Liang Li, Jian-Ying Zeng, Feng Mu, Meng-Tian Liao, Fei Yao, Li Li, Chun-Yan Liu, Ji-Bing Chen, Jian-Sheng Zuo and Ke-Cheng Xu
Funding Agency and Grant Number
Corresponding author Ji-Bing Chen, MD, PhD, Surgical Department, Fuda Cancer Hospital, Jinan University School of Medicine, No. 2 Tangdexi Road, Tianhe District, Guangzhou 510665, Guangdong Province, China. fudaclab@gmail.com
Key Words Cryoablation; Dendritic cell-cytokine-induced killer cell; Immunotherapy; Metastatic hepatocellular cancer; Survival time
Core Tip Fourty-five patients of metastatic hepatocellular cancer were divided into cryo-immunotherapy, cryotherapy, immunotherapy and untreated groups. Median overall survival (OS) was higher following cryo-immunotherapy (32 mo) or cryotherapy (17.5 mo) than in the untreated group (3 mo); In the cryo-immunotherapy group, median OS was higher after multiple treatments (36.5 mo) than after a single treatment (21 mo). In a word, cryotherapy and, especially, cryo-immunotherapy significantly increased OS in metastatic hepatocellular cancer patients. Multiple cryo-immunotherapy was associated with a better prognosis than single cryo-immunotherapy.
Publish Date 2013-06-14 23:10
Citation Niu LZ, Li JL, Zeng JY, Mu F, Liao MT, Yao F, Li L, Liu CY, Chen JB, Zuo JS, Xu KC. Combination treatment with comprehensive cryoablation and immunotherapy in metastatic hepatocellular cancer. World J Gastroenterol 2013; 19(22): 3473-3480
Url http://www.wjgnet.com/1007-9327/full/v19/i22/3473.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i22.3473
Full Article (PDF) WJG-19-3473.pdf
Manuscript File 1597-Review.doc
Answering Reviewers 1597-Answering reviewers.doc
Copyright License Agreement 1597-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 1597-Language certificate.pdf
Peer-review Report 1597-Peer review(s).pdf
Scientific Editor Work List 1597-Scientific editor work list.doc