| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Thrombocytopenia for prediction of hepatocellular carcinoma recurrence: Systematic review and meta-analysis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qing Pang, Kai Qu, Jian-Bin Bi, Su-Shun Liu, Jing-Yao Zhang, Si-Dong Song, Ting Lin, Xin-Sen Xu, Yong Wan, Ming-Hui Tai, Hao-Chen Liu, Ya-Feng Dong and Chang Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81272644 |
| National Natural Science Foundation of China |
81072051 |
|
| Corresponding Author |
Chang Liu, Professor, MD, PhD, Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical College, Xi’an Jiaotong University, No. 277 West Road, Yanta district, Xi’an 710061, Shaanxi Province, China. liuchangdoctor@163.com |
| Key Words |
Hepatocellular carcinoma; Blood platelets; Thrombocytopenia; Recurrence; Prognosis |
| Core Tip |
The probability of high postoperative recurrence is the greatest problem that affects the potential curative treatment of patients with hepatocellular carcinoma (HCC). No factors have been widely considered as useful predictors for postoperative recurrence in HCC. We analyzed 18 relevant studies to determine the significance of platelet count. We included 4163 patients with HCC and found that thrombocytopenia before therapy significantly increased the probability of postoperative recurrence as well as intrahepatic distant recurrence. We emphasize that thrombocytopenia is an inexpensive, helpful predictor of postoperative recurrence in patients with HCC. |
| Publish Date |
2015-07-08 12:01 |
| Citation |
Pang Q, Qu K, Bi JB, Liu SS, Zhang JY, Song SD, Lin T, Xu XS, Wan Y, Tai MH, Liu HC, Dong YF, Liu C. Thrombocytopenia for prediction of hepatocellular carcinoma recurrence: Systematic review and meta-analysis. World J Gastroenterol 2015; 21(25): 7895-7906 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i25/7895.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i25.7895 |
