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1/6/2016 4:13:00 PM | Browse: 1107 | Download: 1443
Publication Name World Journal of Gastroenterology
Manuscript ID 17444
Country/Territory Egypt
Received
2015-03-07 16:26
Peer-Review Started
2015-03-11 17:06
To Make the First Decision
2015-04-13 16:46
Return for Revision
2015-04-16 14:11
Revised
2015-05-16 05:32
Second Decision
2015-09-28 16:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-30 10:07
Articles in Press
2015-09-30 10:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-10-27 04:53
Typeset the Manuscript
2015-12-04 17:05
Publish the Manuscript Online
2016-01-06 16:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Review
Article Title Status of hepatitis C virus vaccination: Recent update
Manuscript Source Invited Manuscript
All Author List Kouka Saadeldin Abdelwahab and Zeinab Nabil Ahmed Said
Funding Agency and Grant Number
Corresponding Author Zeinab Nabil Ahmed Said, Professor, Department of Microbiology and Immunology, Faculty of Medicine (for girls), Al-Azhar University, Nasr City, 8, Ossama Ibn Monkez Street, Heliopolis, Cairo 11435, Egypt. znabil58@yahoo.com
Key Words Hepatitis C; Viral envelope glycoproteins; Immune response; Hepatitis C virus vaccine; Clinical trials
Core Tip Hepatitis C virus (HCV) is a major global public health problem. Chronic HCV infection affected around 130-150 million of the world’s population. The current treatment is expensive, showed some restrictions and is not efficient for all patients. No licensed vaccine is available for clinical use, however, researches on developing a preventive and therapeutic safe vaccine, are evolving. This review gives an overview of HCV structure, immune response and viral evasion mechanisms. It also evaluates the available preventive and therapeutic vaccines that induce innate, antibody-mediated immune response, cell-mediated immune response and interferon, and highlights the progress in recent HCV vaccination studies either in preclinical or clinical phases.
Publish Date 2016-01-06 16:13
Citation Abdelwahab KS, Ahmed Said ZN. Status of hepatitis C virus vaccination: Recent update. World J Gastroenterol 2016; 22(2): 862-873
URL http://www.wjgnet.com/1007-9327/full/v22/i2/862.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i2.862
Full Article (PDF) WJG-22-862.pdf
Full Article (Word) WJG-22-862.doc
Manuscript File 17444-Review.docx
Answering Reviewers 17444-Answering reviewers.pdf
Audio Core Tip 17444-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 17444-Conflict-of-interest statement.pdf
Copyright License Agreement 17444-Copyright assignment.pdf
Supplementary Material Supplementary_Material_20150307030451.docx
Peer-review Report 17444-Peer-review(s).pdf
Scientific Misconduct Check 17444-Scientific misconduct check.pdf
Scientific Editor Work List 17444-Scientific editor work list.pdf