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9/28/2015 6:06:00 PM | Browse: 828 | Download: 773
Publication Name World Journal of Gastroenterology
Manuscript ID 17789
Country/Territory Japan
Received
2015-03-25 12:10
Peer-Review Started
2015-03-27 08:24
To Make the First Decision
2015-04-24 19:21
Return for Revision
2015-04-30 11:07
Revised
2015-05-08 13:01
Second Decision
2015-08-19 14:45
Accepted by Journal Editor-in-Chief
2015-08-20 07:23
Accepted by Company Editor-in-Chief
2015-09-02 15:22
Articles in Press
2015-09-02 15:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-10 14:59
Publish the Manuscript Online
2015-09-28 18:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Mitsuro Kanda, Hiroyuki Sugimoto and Yasuhiro Kodera
Funding Agency and Grant Number
Corresponding Author Mitsuro Kanda, MD, PhD, Department of Gastroenterological Surgery (Surgery Ⅱ), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. m-kanda@med.nagoya-u.ac.jp
Key Words Hepatocellular carcinoma; Oncogene; Tumor suppressor gene; MicroRNA; DNA methylation
Core Tip Despite the large number of studies dedicated to the molecular diagnosis of hepatocellular carcinoma (HCC), highly sensitive biomarkers of the initiation and progression of HCC still need to be identified. At the same time, the development of novel molecular targeting agents that can surpass the effect of the multikinase inhibitor sorafenib is much-anticipated. This review aimed to update our knowledge of genetic and epigenetic aspects of HCC by providing an overview of novel HCC-related genes and microRNAs as candidates for use as diagnostic and therapeutic targets in HCC.
Publish Date 2015-09-28 18:06
Citation Kanda M, Sugimoto H, Kodera Y. Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinoma. World J Gastroenterol 2015; 21(37): 10584-10597
URL http://www.wjgnet.com/1007-9327/full/v21/i37/10584.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i37.10584
Full Article (PDF) WJG-21-10584.pdf
Full Article (Word) WJG-21-10584.doc
Manuscript File 17789-Review.docx
Answering Reviewers 17789-Answering reviewers.pdf
Audio Core Tip 17789-Audio core tip.wav
Conflict-of-Interest Disclosure Form 17789-Conflict-of-interest statement.pdf
Copyright License Agreement 17789-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 17789-Language certificate.pdf
Peer-review Report 17789-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 17789-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 17789-Scientific misconduct check.pdf
Scientific Editor Work List 17789-Scientific editor work list.pdf