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9/28/2015 11:46:00 AM | Browse: 857 | Download: 1313
Publication Name World Journal of Gastroenterology
Manuscript ID 17982
Country/Territory Japan
Received
2015-04-01 16:42
Peer-Review Started
2015-04-02 14:43
To Make the First Decision
2015-06-02 15:29
Return for Revision
2015-06-07 17:55
Revised
2015-06-20 16:58
Second Decision
2015-07-27 20:14
Accepted by Journal Editor-in-Chief
2015-07-29 09:38
Accepted by Company Editor-in-Chief
2015-08-25 18:15
Articles in Press
2015-08-25 18:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-08-31 14:31
Publish the Manuscript Online
2015-09-28 11:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Hepatitis B virus reactivation associated with antirheumatic therapy: risk and prophylaxis recommendations
Manuscript Source Invited Manuscript
All Author List Shunsuke Mori and Shigetoshi Fujiyama
Funding Agency and Grant Number
Funding Agency Grant Number
Research funds from the National Hospital Organization, Japan
Corresponding Author Shunsuke Mori, MD, PhD, Department of Rheumatology, Clinical Research Center for Rheumatic Diseases, NHO Kumamoto Saishunsou National Hospital, 2659 Suya, Kohshi, Kumamoto 861-1196, Japan. moris@saisyunsou1.hosp.go.jp
Key Words Hepatitis B virus; Antirheumatic therapy; Resolved hepatitis B virus infection; Occult hepatitis B virus carrier; Reactivation
Core Tip In the literature, the prevalence of resolved hepatitis B virus (HBV) infection varied in rheumatic disease patients, ranging from 7.3% to 66%, which seems to be related directly to the general prevalence of HBV infection in the respective geographic areas. When calculated using data from observational cohort studies, the incidence rate was 1.7% in rheumatic disease patients receiving biological therapy and 3.2% in those treated with non-biological drugs. In antirheumatic therapy, multiple immunosuppressants are administered during long periods. Optimal frequency and duration of HBV-DNA monitoring and reliable markers for discontinuation of nucleoside analogues remain unclear for rheumatic disease patients with resolved HBV infection.
Publish Date 2015-09-28 11:42
Citation Mori S, Fujiyama S. Hepatitis B virus reactivation associated with antirheumatic therapy: risk and prophylaxis recommendations. World J Gastroenterol 2015; 21(36): 10274-10289
URL http://www.wjgnet.com/1007-9327/full/v21/i36/10274.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i36.10274
Full Article (PDF) WJG-21-10274.pdf
Full Article (Word) WJG-21-10274.doc
Manuscript File 17982-Review.doc
Answering Reviewers 17982-Answering reviewers.pdf
Audio Core Tip 17982-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 17982-Conflict-of-interest statement.pdf
Copyright License Agreement 17982-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 17982-Language certificate.pdf
Peer-review Report 17982-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 17982-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 17982-Scientific misconduct check.pdf
Scientific Editor Work List 17982-Scientific editor work list.pdf