Publication Name	World Journal of Gastroenterology
Manuscript ID	18088
Country	Japan

Received	2015-04-06 16:12
Peer-Review Started	2015-04-07 12:01
To Make the First Decision	2015-06-02 16:12
Return for Revision	2015-06-07 17:59
Revised	2015-06-15 17:44
Second Decision	2015-07-27 20:19
Accepted by Journal Editor-in-Chief	2015-07-30 11:02
Accepted by Company Editor-in-Chief	2015-08-25 18:45
Articles in Press	2015-08-25 18:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-08-28 17:54
Typeset the Manuscript	2015-09-02 11:49
Publish the Manuscript Online	2015-09-28 18:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Does herbal medicine reduce the risk of hepatocellular carcinoma?
Manuscript Source	Invited Manuscript
All Author List	Yasushi Rino, Norio Yukawa and Naoto Yamamoto
Funding Agency and Grant Number
Corresponding Author	Yasushi Rino, MD, Department of Surgery, School of Medicine, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. rino@med.yokohama-cu.ac.jp
Key Words	Herbal medicine; Hepatocellular carcinoma; Anti-inflammatory; Hepatocellular carcinoma prevention; Chronic hepatitis
Core Tip	Many herbal medicines are effective anti-inflammatory agents and may suppress the development of hepatocellular carcinoma (HCC). Patients with chronic hepatitis C generally receive ledipasvir and sofosbuvir worldwide. However, many patients have hepatitis-like fatty liver and nonalcoholic steatohepatitis. A strategy to prevent the development of HCC is urgently required for this subgroup of patients. Future research needs to explore the effectiveness of herbal medicines in preventing and treating HCC. The current lack of knowledge and of educational programs is a barrier to increasing the use of potentially effective herbal medicines and performing prospective clinical trials.
Publish Date	2015-09-28 18:06
Citation	Rino Y, Yukawa N, Yamamoto N. Does herbal medicine reduce the risk of hepatocellular carcinoma? World J Gastroenterol 2015; 21(37): 10598-10603
URL	http://www.wjgnet.com/1007-9327/full/v21/i37/10598.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i37.10598

Full Article (PDF)	WJG-21-10598.pdf
Full Article (Word)	WJG-21-10598.doc
Manuscript File	18088-Review.docx
Answering Reviewers	18088-Answering reviewers.pdf
Audio Core Tip	18088-Audio core tip.wav
Conflict-of-Interest Disclosure Form	18088-Conflict-of-interest statement.pdf
Copyright License Agreement	18088-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18088-Language certificate.pdf
Peer-review Report	18088-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18088-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18088-Scientific misconduct check.pdf
Scientific Editor Work List	18088-Scientific editor work list.pdf