Publication Name	World Journal of Gastroenterology
Manuscript ID	18198
Country	Spain

Received	2015-04-11 10:49
Peer-Review Started	2015-04-11 11:39
To Make the First Decision	2015-05-18 13:11
Return for Revision	2015-05-20 18:58
Revised	2015-05-29 18:50
Second Decision	2015-07-27 19:57
Accepted by Journal Editor-in-Chief	2015-07-27 21:40
Accepted by Company Editor-in-Chief	2015-08-31 16:12
Articles in Press	2015-08-31 16:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-16 11:12
Publish the Manuscript Online	2015-11-03 17:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Immunomodulating effects of antibiotics used in the prophylaxis of bacterial infections in advanced cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Pedro Zapater, José Manuel González-Navajas, José Such and Rubén Francés
Funding Agency and Grant Number	Funding Agency Grant Number Instituto de Salud Carlos III, Madrid, Spain, and FEDER funds, EU PI13/1443 Instituto de Salud Carlos III, Madrid, Spain, and FEDER funds, EU PI14/01090
Corresponding Author	Rubén Francés, PhD, CIBERehd, Hospital General Universitario de Alicante, Avda. Pintor Baeza 12, 03010 Alicante, Spain. frances_rub@gva.es
Key Words	Cirrhosis; Prophylaxis; Cytokines; Bacterial DNA; Norfloxacin
Core Tip	The use of antibiotic therapy to either treat or prevent frequent bacteria-derived complications arising in patients with cirrhosis is well established. The knowledge of antibiotic immunomodulatory mechanism, additional to their bactericidal role, improves our comprehension of the interaction between these molecules and the cellular machinery, and provides insight on the development of alternative strategies in the management and prevention of bacterial infections in cirrhosis.
Publish Date	2015-11-03 17:31
Citation	Zapater P, González-Navajas JM, Such J, Francés R. Immunomodulating effects of antibiotics used in the prophylaxis of bacterial infections in advanced cirrhosis. World J Gastroenterol 2015; 21(41): 11493-11501
URL	http://www.wjgnet.com/1007-9327/full/v21/i41/11493.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i41.11493

Full Article (PDF)	WJG-21-11493.pdf
Full Article (Word)	WJG-21-11493.doc
Manuscript File	18198-Review.docx
Answering Reviewers	18198-Answering reviewers.pdf
Audio Core Tip	18198-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18198-Conflict-of-interest statement.pdf
Copyright License Agreement	18198-Copyright assignment.pdf
Peer-review Report	18198-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18198-Journal editor-in-chief review reportt.pdf
Scientific Misconduct Check	18198-Scientific misconduct check.pdf
Scientific Editor Work List	18198-Scientific editor work list.pdf