Publication Name	World Journal of Hepatology
Manuscript ID	18367
Country	Italy

Received	2015-04-18 11:11
Peer-Review Started	2015-04-19 19:01
To Make the First Decision	2015-06-25 18:14
Return for Revision	2015-06-26 17:24
Revised	2015-06-26 22:31
Second Decision	2015-07-21 19:25
Accepted by Journal Editor-in-Chief	2015-07-21 19:48
Accepted by Company Editor-in-Chief	2015-07-27 16:50
Articles in Press	2015-07-27 16:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-29 17:08
Publish the Manuscript Online	2015-08-08 14:17

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Transarterial chemoembolization: Evidences from the literature and applications in hepatocellular carcinoma patients
Manuscript Source	Invited Manuscript
All Author List	Antonio Facciorusso, Raffaele Licinio, Nicola Muscatiello, Alfredo Di Leo and Michele Barone
Funding Agency and Grant Number
Corresponding Author	Antonio Facciorusso, MD, Gastroen­terology Unit, Department of Medical and Surgical Sciences, University of Foggia, Viale L.Pinto, 1, 71100 Foggia, Italy. antonio.facciorusso@virgilio.it
Key Words	Transarterial chemoembolization; Loco-regional treatment; Hepatocellular carcinoma; Liver cancer; Hepatocarcinoma; Radiofrequency ablation
Core Tip	Transarterial chemoembolization (TACE) represents the standard of care for patients with large or multinodular hepatocellular carcinoma (HCC). However, TACE is a heterogeneous technique varying in terms of chemotherapeutic agents, devices and schedule. In order to overcome these drawbacks of conventional TACE (cTACE), drug-eluting beads have been developed. Unfortunately, despite its theoretical advantages, definitive data in favor of its superiority over cTACE are still lacking. TACE represents the standard-of-care for intermediate-stage HCC, in competition with other therapeutic options (surgery and radioembolization). Other fields of application are the pre-transplant setting and the early stage (in patients unsuitable to curative therapy).
Publish Date	2015-08-08 14:17
Citation	Facciorusso A, Licinio R, Muscatiello N, Di Leo A, Barone M. Transarterial chemoembolization: Evidences from the literature and applications in hepatocellular carcinoma patients. World J Hepatol 2015; 7(16): 2009-2019
URL	http://www.wjgnet.com/1948-5182/full/v7/i16/2009.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i16.2009

Full Article (PDF)	WJH-7-2009.pdf
Full Article (Word)	WJH-7-2009.doc
Manuscript File	18367-Review.docx
Answering Reviewers	18367-Answering reviewers.pdf
Audio Core Tip	18367-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18367-Conflict-of-interest statement.pdf
Copyright License Agreement	18367-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18367-Language certificate.pdf
Peer-review Report	18367-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18367-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18367-Scientific misconduct check.pdf
Scientific Editor Work List	18367-Scientific editor work list.pdf