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8/26/2015 8:56:00 PM | Browse: 1183 | Download: 1917
Publication Name World Journal of Diabetes
Manuscript ID 18617
Country United States
Received
2015-04-25 10:45
Peer-Review Started
2015-04-28 16:43
To Make the First Decision
2015-06-03 14:21
Return for Revision
2015-06-09 11:25
Revised
2015-06-15 23:41
Second Decision
2015-08-12 18:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-08-17 12:01
Articles in Press
2015-08-17 12:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-08-22 19:46
Publish the Manuscript Online
2015-08-26 20:56
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Basic Study
Article Title Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats
Manuscript Source Invited Manuscript
All Author List María J Crespo and José Quidgley
Funding Agency and Grant Number
Funding Agency Grant Number
MBRS-RISE R25-GM061838
RCMI G12-RR03051
Corresponding Author Dr. María J Crespo, Departments of Physiology and Anesthesiology, University of Puerto Rico School of Medicine, GPO Box 365067, San Juan, PR 00936 5067, United States. maria.crespo3@upr.edu
Key Words Statins; Diabetes; Oxidative stress; Cardiac function; Perivascular fibrosis
Core Tip Despite evidence that statins are useful therapeutic tools in treating diabetes, questions remain as to whether their effects are drug-specific or class-dependent, what mechanisms underlie these effects, and which statin is the most appropriate. We found that atorvastatin, simvastatin, and pravastatin are equally effective in improving cardiovascular performance in Type 1 diabetic rats, and that the observed benefits are likely to be secondary to the reduction of oxidative stress by these drugs.
Publish Date 2015-08-26 20:56
Citation Crespo MJ, Quidgley J. Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats. World J Diabetes 2015; 6(10): 1168-1178
URL http://www.wjgnet.com/1948-9358/full/v6/i10/1168.htm
DOI http://dx.doi.org/10.4239/wjd.v6.i10.1168
Full Article (PDF) WJD-6-1168.pdf
Full Article (Word) WJD-6-1168.doc
Manuscript File 18617-Review.docx
Answering Reviewers 18617-Answering reviewers.pdf
Audio Core Tip 18617-Audio core tip.wav
Biostatistics Review Certificate 18617-Biostatistics statement.PDF
Conflict-of-Interest Disclosure Form 18617-Conflict-of-interest statement.PDF
Copyright License Agreement 18617-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 18617-Institutional animal care and use committee statement.PDF
Institutional Review Board Approval Form or Document 18617-Institutional review board statement.pdf
Peer-review Report 18617-Peer-review(s).pdf
Scientific Misconduct Check 18617-Scientific misconduct check.pdf
Scientific Editor Work List 18617-Scientific editor work list.pdf