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12/31/2015 1:27:00 PM | Browse: 1227 | Download: 1755
Publication Name World Journal of Gastroenterology
Manuscript ID 18818
Country/Territory Germany
Received
2015-04-28 16:44
Peer-Review Started
2015-05-04 11:00
To Make the First Decision
2015-08-26 09:48
Return for Revision
2015-09-14 21:03
Revised
Second Decision
2015-11-03 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-11-13 15:59
Articles in Press
2015-11-13 15:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-11-19 21:36
Typeset the Manuscript
2015-12-13 21:29
Publish the Manuscript Online
2015-12-31 13:27
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Topic Highlights
Article Title Genetic variation of hepatitis B virus and its significance for pathogenesis
Manuscript Source Invited Manuscript
All Author List Zhen-Hua Zhang, Chun-Chen Wu, Xin-Wen Chen, Xu Li, Jun Li and Meng-Ji Lu
Funding Agency and Grant Number
Corresponding Author Meng-Ji Lu, PhD, Institute of Virology, University Hospital of Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany. mengji.lu@uni-due.de
Key Words Hepatitis B virus; Genotype; Variation; Pathogenesis
Core Tip Due to the unique life cycle of hepatitis B virus (HBV) which requires an error-prone reverse transcriptase for replication, it constantly evolves resulting in significant genetic variation in the form of genotype, sub-genotype, and mutations. A large number of publications on the relationship between HBV genetic variation and HBV-related pathogenesis have appeared in recent years. However, the progress in this field has not been reviewed. We have attempted to provide a brief account of the influence of HBV genotype and mutations in the different viral genome regions on HBV-associated pathogenesis. This review provides an overview for scientists working on HBV and related fields.
Publish Date 2015-12-31 13:27
Citation Zhang ZH, Wu CC, Chen XW, Li X, Li J, Lu MJ. Genetic variation of hepatitis B virus and its significance for pathogenesis. World J Gastroenterol 2016; 22(1): 126-144
URL http://www.wjgnet.com/1007-9327/full/v22/i1/126.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i1.126
Full Article (PDF) WJG-22-126.pdf
Full Article (Word) WJG-22-126.doc
Manuscript File 18818-Review.docx
Answering Reviewers 18818-Answering reviewers.pdf
Audio Core Tip 18818-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 18818-Conflict-of-interest statement.pdf
Copyright License Agreement 18818-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 18818-Language certificate.pdf
Peer-review Report 18818-Peer-review(s).pdf
Scientific Misconduct Check 18818-Scientific misconduct check.pdf
Scientific Editor Work List 18818-Scientific editor work list.pdf