Publication Name	World Journal of Gastroenterology
Manuscript ID	18859
Country	Netherlands

Received	2015-04-30 15:24
Peer-Review Started	2015-05-05 21:11
To Make the First Decision	2015-08-26 09:52
Return for Revision	2015-09-01 17:36
Revised	2015-10-12 02:35
Second Decision	2015-11-11 16:53
Accepted by Journal Editor-in-Chief	2015-11-11 21:59
Accepted by Executive Editor-in-Chief	2015-12-01 08:07
Articles in Press	2015-12-01 08:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-28 17:31
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Cytomegalovirus in inflammatory bowel disease: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Tessa EH Römkens, Geert J Bulte, Loes HC Nissen and Joost PH Drenth
Funding Agency and Grant Number
Corresponding Author	Tessa EH Römkens, MD, Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. tessa.romkens@radboudumc.nl
Key Words	Inflammatory bowel disease; Cyto­megalovirus; Ulcerative colitis; Crohn’s disease; Sys­tematic review
Core Tip	The use of different definitions for cyto-megalovirus (CMV) infection and CMV intestinal disease in inflammatory bowel disease (IBD) patients has great impact on the reported prevalence rates (definitions with highest prevalence: positive serum PCR (CMV infection) and tissue PCR > 10 copies/mg tissue (CMV intestinal disease)). In addition, prevalence rates depend on the studied population (highest prevalence: steroid refractory disease), and region (highest prevalence: East Asia). Our key message is not to develop more sensitive diagnostics to find CMV, but to organise a global consensus meeting on CMV in IBD to formulate one unified definition for clinically relevant CMV (intestinal) disease in IBD.
Publish Date	2016-01-15 14:54
Citation	Römkens TEH, Bulte GJ, Nissen LHC, Drenth JPH. Cytomegalovirus in inflammatory bowel disease: A systematic review. World J Gastroenterol 2016; 22(3): 1321-1330
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/1321.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.1321

Full Article (PDF)	WJG-22-1321.pdf
Full Article (Word)	WJG-22-1321.doc
Manuscript File	18859-Review.docx
Answering Reviewers	18859-Answering reviewers.pdf
Audio Core Tip	18859-Audio core tip.mp3
Biostatistics Review Certificate	18859-Biostatistics statement.pdf
Clinical Trial Registration Statement	DeclarationOf_HelsinkiConformation_Statement_20150428015427.pdf
Conflict-of-Interest Disclosure Form	18859-Conflict-of-interest statement.pdf
Copyright License Agreement	18859-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18859-Language certificate.pdf
Supplementary Material	18859-Supplementary material.pdf
Peer-review Report	18859-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18859-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18859-Scientific misconduct check.pdf
Scientific Editor Work List	18859-Scientific editor work list.pdf