Publication Name	World Journal of Gastroenterology
Manuscript ID	18957
Country	China

Received	2015-04-29 14:20
Peer-Review Started	2015-05-05 09:38
To Make the First Decision	2015-09-11 08:58
Return for Revision	2015-09-15 13:48
Revised	2015-09-30 17:04
Second Decision	2015-11-03 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-11-13 15:59
Articles in Press	2015-11-13 15:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-18 15:03
Typeset the Manuscript	2016-01-04 17:57
Publish the Manuscript Online	2016-01-20 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Host restriction factors for hepatitis C virus
Manuscript Source	Invited Manuscript
All Author List	Li-Ya Zhou and Lei-Liang Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81271832 (to Zhang LL) National Natural Science Foundation of China 81471955 (to Zhang LL)
Corresponding Author	Lei-Liang Zhang, PhD, MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 9, Dongdan Santiao, Dongcheng District, Beijing 100730, China. armzhang@hotmail.com
Key Words	Hepatitis C virus; Host restriction factor; Interferon; Entry; Replication; Propagation
Core Tip	Hepatitis C is a liver disease caused by the hepatitis C virus (HCV), which chronically infects approximately 130-150 million people. The ultimate outcome of HCV infection depends on host-viral interactions. Host cells encode multiple proteins to suppress HCV infection, known as host restriction factors. In this review, we will summarize the host restriction factors in different steps of the HCV life cycle. The possible mechanisms of the host restriction factors will also be discussed.
Publish Date	2016-01-20 16:55
Citation	Zhou LY, Zhang LL. Host restriction factors for hepatitis C virus. World J Gastroenterol 2016; 22(4): 1477-1486
URL	http://www.wjgnet.com/1007-9327/full/v22/i4/1477.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i4.1477

Full Article (PDF)	WJG-22-1477.pdf
Full Article (Word)	WJG-22-1477.doc
Manuscript File	18957-Review.doc
Answering Reviewers	18957-Answering reviewers.doc
Audio Core Tip	18957-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18957-Conflict-of-interest statement.pdf
Copyright License Agreement	18957-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18957-Language certificate.pdf
Peer-review Report	18957-Peer-review(s).pdf
Scientific Misconduct Check	18957-Scientific misconduct check.pdf
Scientific Editor Work List	18957-Scientific editor work list.pdf