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9/9/2015 2:44:00 PM | Browse: 963 | Download: 1284
Publication Name World Journal of Hepatology
Manuscript ID 19211
Country/Territory United States
Received
2015-04-30 13:01
Peer-Review Started
2015-05-07 18:00
To Make the First Decision
2015-06-29 18:15
Return for Revision
2015-07-01 08:52
Revised
2015-07-28 11:14
Second Decision
2015-08-13 10:09
Accepted by Journal Editor-in-Chief
2015-08-13 13:10
Accepted by Company Editor-in-Chief
2015-08-21 16:08
Articles in Press
2015-08-21 16:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-08-26 08:51
Publish the Manuscript Online
2015-09-09 14:44
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Chronic hepatitis E: A brief review
Manuscript Source Invited Manuscript
All Author List Arvind R Murali, Vikram Kotwal and Saurabh Chawla
Funding Agency and Grant Number
Corresponding Author Saurabh Chawla, MD, Assistant Professor of Medicine, Director of Interventional Endoscopy, Grady Memorial Hospital and Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Faculty Office Building, 49 Jesse Hill Jr. Drive, Suite 431, Atlanta, GA 30322, United States. saurabh.chawla@emory.edu
Key Words Hepatitis E virus; Chronic liver disease; Solid organ transplantation; Hematological malignancies; Immunosuppression
Core Tip Chronic hepatitis E occurs mainly in immuno-suppressed individuals such as transplant recipients, human immunodeficiency virus patients with low CD4 counts and in patients with hematological maligna-ncies receiving chemotherapy. A few cases have also been reported in immunocompetent individuals. These patients may present with unexplained elevation in transaminases or less frequently with neurological or renal manifestations. The diagnosis is confirmed by a persistent elevation of hepatitis E RNA in serum or stool. Reduction of immunosuppression to achieve spontaneous viral clearance should be attempted. However it is effective only in about a third of patients, therefore most patients require treatment with antiviral agents, like ribavirin. The purpose of this review is to increase awareness amongst physicians of chronic hepatitis E infection as a possible treatable cause of chronic liver disease, especially in immunosuppressed individuals.
Publish Date 2015-09-09 14:44
Citation Murali AR, Kotwal V, Chawla S. Chronic hepatitis E: A brief review. World J Hepatol 2015; 7(19): 2194-2201
URL http://www.wjgnet.com/1948-5182/full/v7/i19/2194.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i19.2194
Full Article (PDF) WJH-7-2194.pdf
Full Article (Word) WJH-7-2194.doc
Manuscript File 19211-Review.docx
Answering Reviewers 19211-Answering reviewers.pdf
Audio Core Tip 19211-Audio core tip.wma
Conflict-of-Interest Disclosure Form 19211-Conflict-of-interest statement.pdf
Copyright License Agreement 19211-Copyright assignment.pdf
Peer-review Report 19211-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 19211-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 19211-Scientific misconduct check.pdf
Scientific Editor Work List 19211-Scientific editor work list.pdf