Publication Name	World Journal of Gastroenterology
Manuscript ID	19384
Country	Italy

Received	2015-05-06 08:30
Peer-Review Started	2015-05-11 10:46
To Make the First Decision	2015-08-31 08:15
Return for Revision	2015-09-02 10:27
Revised	2015-09-18 19:39
Second Decision	2015-11-19 09:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-01 08:30
Articles in Press	2015-12-01 08:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-04 20:34
Publish the Manuscript Online	2016-01-20 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Vertically acquired hepatitis C virus infection: Correlates of transmission and disease progression
Manuscript Source	Invited Manuscript
All Author List	Pier-Angelo Tovo, Carmelina Calitri, Carlo Scolfaro, Clara Gabiano and Silvia Garazzino
Funding Agency and Grant Number
Corresponding Author	Dr. Pier-Angelo Tovo, MD, Professor of Pediatrics, Department of Pediatrics, University of Turin, Ospedale Infantile Regina Margherita, Piazza Polonia 94, 10126 Torino, Italy. pierangelo.tovo@unito.it
Key Words	Hepatitis C virus; Vertical transmission; Risk factors; Spontaneous viral clearance; Disease progression; Pediatrics
Core Tip	Approximately 5% of exposed infants acquire hepatitis C virus (HCV) infection from the mother. Several correlates of vertical transmission have been identified, but no preventive intervention is available. Spontaneous viral clearance takes place in 25% of infected children within 6 years of age. Chronic infection has a mild/moderate course in the majority of children, though severe liver damage may develop. The new direct acting antiviral agents open exciting therapeutic perspectives for HCV infected children and offer an immediate opportunity to prevent the vertical transmission by reducing the burden of infected women of child-bearing age.
Publish Date	2016-01-20 16:55
Citation	Tovo PA, Calitri C, Scolfaro C, Gabiano C, Garazzino S. Vertically acquired hepatitis C virus infection: Correlates of transmission and disease progression. World J Gastroenterol 2016; 22(4): 1382-1392
URL	http://www.wjgnet.com/1007-9327/full/v22/i4/1382.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i4.1382

Full Article (PDF)	WJG-22-1382.pdf
Full Article (Word)	WJG-22-1382.doc
Manuscript File	19384-Review.docx
Answering Reviewers	19384-Answering reviewers.pdf
Audio Core Tip	19384-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19384-Conflict-of-interest statement.pdf
Copyright License Agreement	19384-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19384-Language certificate.pdf
Peer-review Report	19384-Peer-review(s).pdf
Scientific Misconduct Check	19384-Scientific misconduct check.pdf
Scientific Editor Work List	19384-Scientific editor work list.pdf