Publication Name	World Journal of Gastroenterology
Manuscript ID	1962
Country	South Korea

Received	2013-01-17 12:16
Peer-Review Started	2013-01-17 15:05
To Make the First Decision	2013-03-18 15:24
Return for Revision	2013-04-22 11:58
Revised
Second Decision	2013-07-01 12:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-07-01 23:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-07-18 14:55
Typeset the Manuscript	2013-07-31 10:58
Publish the Manuscript Online	2013-08-13 11:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Low-dose amitriptyline combined with proton pump inhibitor for functional chest pain
Manuscript Source	Invited Manuscript
All Author List	Se Woo Park, Hyuk Lee, Hyun Jik Lee, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee and Ji Eun Kim
Funding Agency and Grant Number
Corresponding Author	Hyuk Lee, MD, Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. leehyuk@yuhs.ac
Key Words	Functional chest pain; Proton pump inhibitor; Amitriptyline
Core Tip	Hypersensitivity and psychological problems have an important role in the pathogenesis of functional chest pain (FCP). In this regard, the principal treatment of FCP has moved towards hypersensitivity modulation and antidepressant agents on the basis that the underlying mechanisms were increased pain perception or visceral hyperalgesia in addition to psychologic causes. This is the first study to report that adding low-dose amitriptyline to a conventional dose of proton pump inhibitor (PPI) is more effective than a double-dose of PPI in patients with FCP resistant to a conventional dose of PPI treatment.
Publish Date	2013-08-13 11:13
Citation	Park SW, Lee H, Lee HJ, Park JC, Shin SK, Lee SK, Lee YC, Kim JE. Low-dose amitriptyline combined with proton pump inhibitor for functional chest pain. World J Gastroenterol 2013; 19(30): 4958-4965
URL	http://www.wjgnet.com/1007-9327/full/v19/i30/4958.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i30.4958

Full Article (PDF)	WJG-19-4958.pdf
Manuscript File	1962-Review.doc
Answering Reviewers	1962-Answering reviewers.pdf
Copyright License Agreement	1962-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	1962-Language certificate.pdf
Peer-review Report	1962-Peer review(s).pdf
Scientific Editor Work List	1962-Scientific editor work list.doc