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12/31/2015 1:27:00 PM | Browse: 632 | Download: 797
Publication Name World Journal of Gastroenterology
Manuscript ID 19712
Country/Territory Japan
2015-05-19 09:11
Peer-Review Started
2015-05-20 08:01
To Make the First Decision
2015-08-26 10:04
Return for Revision
2015-08-27 11:03
2015-11-11 01:17
Second Decision
2015-12-01 10:37
Accepted by Journal Editor-in-Chief
2015-12-02 20:07
Accepted by Company Editor-in-Chief
2015-12-14 15:54
Articles in Press
2015-12-14 15:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-12-21 10:10
Publish the Manuscript Online
2015-12-31 13:27
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Topic Highlights
Article Title Prophylactic managements of hepatitis B viral infection in liver transplantation
Manuscript Source Invited Manuscript
All Author List Takashi Onoe, Hiroyuki Tahara, Yuka Tanaka and Hideki Ohdan
Funding Agency and Grant Number
Funding Agency Grant Number
Japanese Ministry of Health, Labour and Welfare for the Research of Hepatitis and BSE
Corresponding Author Dr. Takashi Onoe, MD, PhD, Head, Division of Applied Immunobiology, Institute for Clinical Research, National Hospital Organization, Kure Medical Center/Chugoku Cancer Center, 3-1 Aoyama-cho, Kure, Hiroshima 737-0023, Japan. tonoemd@gmail.com
Key Words Liver transplantation; Hepatitis B infection; prophylaxis; nucleos(t)ide analogue; anti-hepatitis B immunoglobulin
Core Tip Combination therapy consisting of high-dose hepatitis B immunoglobulin (HBIG) and lamivudine has been the standard prophylaxis for hepatitis B virus recurrence after liver transplantation. Currently, after development of more potent high genetic barrier nucleos(t)ide analogues (hgbNAs), such as entecavir and tenofovir disoproxil fumarate, combination therapy using low-dose HBIG and hgbNA is considered as the most efficacious and cost-effective prophylaxis. In addition, monotherapy with hgbNAs and withdrawal of HBIG following combination therapy of HBIG and hgbNAs could be promising approaches, especially for low-risk patients and those receiving grafts from hepatitis B core antibody-positive donors. This review discusses those approaches including other challenging therapeutic options.
Publish Date 2015-12-31 13:27
Citation Onoe T, Tahara H, Tanaka Y, Ohdan H. Prophylactic managements of hepatitis B viral infection in liver transplantation. World J Gastroenterol 2016; 22(1): 165-175
Url http://www.wjgnet.com/1007-9327/full/v22/i1/165.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i1.165
Full Article (PDF) WJG-22-165.pdf
Full Article (Word) WJG-22-165.doc
Manuscript File 19712-Review.docx
Answering Reviewers 19712-Answering reviewers.pdf
Audio Core Tip 19712-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 19712-Conflict-of-interest statement.pdf
Copyright License Agreement 19712-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 19712-Language certificate.pdf
Peer-review Report 19712-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 19712-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 19712-Scientific misconduct check.pdf
Scientific Editor Work List 19712-Scientific editor work list.pdf