Publication Name	World Journal of Gastroenterology
Manuscript ID	20021
Country	Hungary

Received	2015-05-28 10:49
Peer-Review Started	2015-05-31 11:38
To Make the First Decision	2015-07-14 11:48
Return for Revision	2015-07-27 18:56
Revised	2015-09-14 22:00
Second Decision	2015-10-23 16:38
Accepted by Journal Editor-in-Chief	2015-10-26 09:05
Accepted by Company Editor-in-Chief	2015-11-09 17:23
Articles in Press	2015-11-09 17:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-02 15:32
Publish the Manuscript Online	2015-12-31 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Proteoglycans in liver cancer
Manuscript Source	Invited Manuscript
All Author List	Kornélia Baghy, Péter Tátrai, Eszter Regős and Ilona Kovalszky
Funding Agency and Grant Number	Funding Agency Grant Number Hungarian Research Fund (OTKA) 100904 (to Kovalszky I) Hungarian Research Fund (OTKA) 105763 (to Baghy K)
Corresponding Author	Ilona Kovalszky, MD, PhD, DSc, First Department of Pathology and Experimental Cancer Research, Semmelweis University, 26 Üllői Street, H1085 Budapest, Hungary. koval@korb1.sote.hu
Key Words	Cancer; Cell regulation; Heparan sulfate; Liver; Proteoglycans
Core Tip	Proteoglycans are molecules that contain at least one glycosaminoglycan chain and are primarily found on the cell surface and in the extracellular matrix, where they serve as structural components. In addition, their glycosaminoglycan chains interact with numerous regulatory molecules, thus potentially influencing a myriad of cellular processes, including those linked with cancer development. For example, they can support or inhibit signaling of growth factors, cytokines, and hormones. This article reviews current data demonstrating the versatile role of proteoglycans in the development, maintenance, and progression of liver cancer.
Publish Date	2015-12-31 13:27
Citation	Baghy K, Tátrai P, Regős E, Kovalszky I. Proteoglycans in liver cancer. World J Gastroenterol 2016; 22(1): 379-393
URL	http://www.wjgnet.com/1007-9327/full/v22/i1/379.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i1.379

Full Article (PDF)	WJG-22-379.pdf
Full Article (Word)	WJG-22-379.doc
Manuscript File	20021-Review.docx
Answering Reviewers	20021-Answering reviewers.pdf
Audio Core Tip	20021-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20021-Conflict-of-interest statement.pdf
Copyright License Agreement	20021-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20021-Language certificate.pdf
Peer-review Report	20021-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20021-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20021-Scientific misconduct check.pdf
Scientific Editor Work List	20021-Scientific editor work list.pdf