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12/31/2015 1:27:00 PM | Browse: 888 | Download: 1171
Publication Name World Journal of Gastroenterology
Manuscript ID 20036
Country/Territory China
Received
2015-05-28 10:02
Peer-Review Started
2015-05-29 12:00
To Make the First Decision
2015-08-31 08:54
Return for Revision
2015-08-31 16:08
Revised
2015-09-14 00:00
Second Decision
2015-09-23 19:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-30 08:46
Articles in Press
2015-09-30 08:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-10-26 22:57
Typeset the Manuscript
2015-12-10 20:15
Publish the Manuscript Online
2015-12-31 13:27
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Topic Highlights
Article Title Targeting adeno-associated virus and adenoviral gene therapy for hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Yi-Gang Wang, Pan-Pan Huang, Rong Zhang, Bu-Yun Ma, Xiu-Mei Zhou and Yan-Fang Sun
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81272687
Zhejiang Provincial Public Welfare Technology Application Research Projects 2014C33275
Zhejiang Provincial Natural Science Foundation of China LZ13H160004
the Grant for 521 Talent Project of Zhejiang Sci-Tech University
Corresponding Author Dr. Yi-Gang Wang, Xinyuan Institute of Medicine and Biotechnology, School of Life Sciences, Zhejiang Sci-Tech University, No. 5, Road 2, Xiasha District, Hangzhou 310018, Zhejiang Province, China. wangyigang43@163.com
Key Words Hepatocellular carcinoma; Adeno-associated virus; Adenovirus; Virus vectors
Core Tip This review summarizes the basic knowledge, current advances, and future challenges and prospects of adeno-associated virus (AAV) and adenoviruses as vectors for gene therapy of hepatocellular carcinoma. This paper also reviews the clinical trials of gene therapy using adenovirus vectors, immunotherapy, toxicity and immunological barriers for AAV and adenoviruses, and proposes several alternative strategies to overcome the therapeutic barriers to using AAV and adenoviruses as vectors.
Publish Date 2015-12-31 13:27
Citation Wang YG, Huang PP, Zhang R, Ma BY, Zhou XM, Sun YF. Targeting adeno-associated virus and adenoviral gene therapy for hepatocellular carcinoma. World J Gastroenterol 2016; 22(1): 326-337
URL http://www.wjgnet.com/1007-9327/full/v22/i1/326.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i1.326
Full Article (PDF) WJG-22-326.pdf
Full Article (Word) WJG-22-326.doc
Manuscript File 20036-Review.doc
Answering Reviewers 20036-Answering reviewers.pdf
Audio Core Tip 20036-Audio core tip.MP3
Conflict-of-Interest Disclosure Form 20036-Conflict-of-interest statement.pdf
Copyright License Agreement 20036-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 20036-Language certificate.PDF
Peer-review Report 20036-Peer-review(s).pdf
Scientific Editor Work List 20036-Scientific editor work list.pdf