Publication Name	World Journal of Gastroenterology
Manuscript ID	20100
Country	China

Received	2015-05-28 16:39
Peer-Review Started	2015-05-31 16:10
To Make the First Decision	2015-09-11 08:58
Return for Revision	2015-09-15 16:14
Revised	2015-10-03 08:36
Second Decision	2015-11-03 09:18
Accepted by Journal Editor-in-Chief	2015-11-05 18:02
Accepted by Company Editor-in-Chief	2015-11-13 16:02
Articles in Press	2015-11-13 16:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-18 20:31
Typeset the Manuscript	2015-12-21 10:06
Publish the Manuscript Online	2015-12-31 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Allergy
Manuscript Type	Topic Highlights
Article Title	Naturally derived anti-hepatitis B virus agents and their mechanism of action
Manuscript Source	Invited Manuscript
All Author List	Yi-Hang Wu
Funding Agency and Grant Number	Funding Agency Grant Number Zhejiang Provincial Natural Science Foundation of China LY14H310010 Public Welfare Technology Applied Research Project of Zhejiang Province-Experimental Animal Science and Technology Project 2013C37020 Key Project of Chinese Ministry of Education 212073
Corresponding Author	Yi-Hang Wu, Professor, Zhejiang Provincial Key Laboratory of Biometrology and Inspection and Quarantine, Department of Pharmacy, College of Life Sciences, China Jiliang University, No. 258 Xueyuan Street, Hangzhou 310018, Zhejiang Province, China. yihangwu@126.com
Key Words	Natural product; Hepatitis B virus; Structure; Mechanism of action; Drug target
Core Tip	Hepatitis B virus (HBV) infection continues to be a significant health problem in the world. The urgent need for new anti-HBV drugs is a global concern. Naturally originated compounds with various skeletons and diverse biological activities provide a large reservoir for finding novel anti-HBV leads or candidates. In this review, the anti-HBV natural products are classified according to their structure types such as terpenes, lignans, phenolic acids, polyphenols, lactones, alkaloids and flavonoids. Furthermore, novel mode of action or new targets of some representative anti-HBV natural products are also discussed.
Publish Date	2015-12-31 13:27
Citation	Wu YH. Naturally derived anti-hepatitis B virus agents and their mechanism of action. World J Gastroenterol 2016; 22(1): 188-204
URL	http://www.wjgnet.com/1007-9327/full/v22/i1/188.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i1.188

Full Article (PDF)	WJG-22-188.pdf
Full Article (Word)	WJG-22-188.doc
Manuscript File	20100-Review.doc
Answering Reviewers	20100-Answering reviewers.pdf
Audio Core Tip	20100-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20100-Conflict-of-interest statement.pdf
Copyright License Agreement	20100-Copyright assignment.pdf
Peer-review Report	20100-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20100-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20100-Scientific misconduct check.pdf
Scientific Editor Work List	20100-Scientific editor work list.pdf