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1/29/2016 11:06:00 AM | Browse: 1242 | Download: 1349
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 20128
Country/Territory Greece
Received
2015-05-29 09:37
Peer-Review Started
2015-06-01 07:58
To Make the First Decision
2015-10-14 11:19
Return for Revision
2015-10-15 10:26
Revised
2015-10-20 17:41
Second Decision
2015-11-23 17:58
Accepted by Journal Editor-in-Chief
2015-11-23 23:06
Accepted by Company Editor-in-Chief
2015-12-04 16:10
Articles in Press
2015-12-04 16:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-01-18 20:35
Publish the Manuscript Online
2016-01-29 11:06
ISSN 2150-5349 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Influence of environmental factors in the development of inflammatory bowel diseases
Manuscript Source Invited Manuscript
All Author List Evangelia Legaki and Maria Gazouli
Funding Agency and Grant Number
Funding Agency Grant Number
Hellenic State Scholarships Foundation to Legaki E
Corresponding Author Maria Gazouli, PhD, Assistant Professor, Department of Basic Medical Sciences, Laboratory of Biology, School of Medicine, University of Athens, Michalakopoulou 176, 11527 Athens, Greece. mgazouli@med.uoa.gr
Key Words Crohn’s disease; Ulcerative colitis; Epigenetics; Environment
Core Tip Epidemiological data, clinical observations and family/ immigrants studies indicate the significance of environmental influence in the development of inflammatory bowel diseases (IBD). A westernized high fat diet, full of refined carbohydrates is strongly associated with the development of IBD, contrary to a high in fruit, vegetables and polyunsaturated fatty acid-3 diet that is protective against these diseases. Additional factors such as air pollution, psychological factors, sleep disturbances and exercise influence the development and the course of IBD. Epigenetic mechanism like DNA methylation, histone modification and altered expression of miRNAS could explain the connection between genes and environmental factors in triggering the development of IBD.
Publish Date 2016-01-29 11:06
Citation Legaki E, Gazouli M. Influence of environmental factors in the development of inflammatory bowel diseases. World J Gastrointest Pharmacol Ther 2016; 7(1): 112-125
URL http://www.wjgnet.com/2150-5349/full/v7/i1/112.htm
DOI http://dx.doi.org/10.4292/wjgpt.v7.i1.112
Full Article (PDF) WJGPT-7-112.pdf
Full Article (Word) WJGPT-7-112.doc
Manuscript File 20128-Review.doc
Answering Reviewers 20128-Answering reviewers.pdf
Audio Core Tip 20128-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 20128-Conflict-of-interest statement.pdf
Copyright License Agreement 20128-Copyright assignmet.pdf
Peer-review Report 20128-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 20128-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 20128-Scientific misconduct check.pdf
Scientific Editor Work List 20128-Scientific editor work list.pdf