Publication Name	World Journal of Clinical Oncology
Manuscript ID	20197
Country	Italy

Received	2015-05-29 20:39
Peer-Review Started	2015-06-02 19:07
To Make the First Decision	2015-07-27 18:38
Return for Revision	2015-07-31 19:30
Revised	2015-08-22 18:34
Second Decision	2015-11-09 10:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-11-25 16:29
Articles in Press	2015-11-25 16:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-18 21:50
Publish the Manuscript Online	2016-01-30 17:42

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians
Manuscript Source	Invited Manuscript
All Author List	Rosella Spadi, Federica Brusa, Agostino Ponzetti, Isabella Chiappino, Nadia Birocco, Libero Ciuffreda and Maria Antonietta Satolli
Funding Agency and Grant Number
Corresponding Author	Rosella Spadi, MD, Consultant Medical Oncologist, Department of Oncology, Azienda Ospedaliera Città della Salute e della Scienza, corso Bramante 88, 10126 Torino, Italy. rosella.spadi@libero.it
Key Words	Pancreatic cancer; Chemotherapy; Radio-frequency; Stereotactic radiotherapy; Irreversible electroporation
Core Tip	This review focuses on the current clinical practice in the treatment of pancreatic cancer (PC), and outlines research topics. PC is still a highly lethal disease, for a usual presentation stage not manageable with curative surgery. Up to now, new targeted therapies have not shown any positive impact on its dismal prognosis. Only slight improvements ensued from the availability of more active polychemotherapy regimens. From the point of view of a multimodal approach, in addition to surgery, new locoregional techniques are nowadays available, suitable for combination with systemic treatments, to increase disease control and survival.
Publish Date	2016-01-30 17:42
Citation	Spadi R, Brusa F, Ponzetti A, Chiappino I, Birocco N, Ciuffreda L, Satolli MA. Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians. World J Clin Oncol 2016; 7(1): 27-43
URL	http://www.wjgnet.com/2218-4333/full/v7/i1/27.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i1.27

Full Article (PDF)	WJCO-7-27.pdf
Full Article (Word)	WJCO-7-27.doc
Manuscript File	1 20197 Revised manuscript.doc
Answering Reviewers	2 20197 Answering reviewers.doc
Audio Core Tip	4 20197 Audio core tip.wma
Conflict-of-Interest Disclosure Form	4 20197 Conflict of interest statement.pdf
Copyright License Agreement	3 20197 Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8 20197 Language certificate .doc
Peer-review Report	20197-Peer-review(s).pdf
Scientific Editor Work List	20197-Scientific editor work list.pdf