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3/4/2016 7:53:00 PM | Browse: 1145 | Download: 2476
Publication Name World Journal of Gastroenterology
Manuscript ID 20549
Country/Territory Egypt
Received
2015-06-10 08:49
Peer-Review Started
2015-06-12 10:15
To Make the First Decision
2015-11-05 10:47
Return for Revision
2015-11-06 09:24
Revised
2015-12-04 03:24
Second Decision
2015-12-31 07:56
Accepted by Journal Editor-in-Chief
2016-01-01 20:30
Accepted by Company Editor-in-Chief
2016-01-11 13:05
Articles in Press
2016-01-11 13:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-02-26 09:29
Publish the Manuscript Online
2016-03-04 19:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Basic Study
Article Title Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression
Manuscript Source Unsolicited Manuscript
All Author List Enas A Abd El-Haleim, Ashraf K Bahgat and Samira Saleh
Funding Agency and Grant Number
Corresponding Author Enas A Abd El-Haleim, MSc, Assistant Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo University Rd, Cairo 11562, Egypt. enaselshemy@hotmail.com
Key Words Fructose; Nonalcoholic steatohepatitis; Suppressor of cytokine signaling-3; Sterol regulatory element binding protein-1c; Fatty acid synthase; Malonyl CoA decarboxylase; Leptin; Adiponectin; Transforming growth factor-β; Tumor necrosis factor-α
Core Tip The current work may justify the use of lower doses of fenofibrate in combination with resveratrol to protect the liver from fructose induced hepatic steatosis and damage. The synergistic effect may be due to antioxidant, anti-inflammatory and anti-hyperlipidemic effect of resveratrol. As an add-on therapy, resveratrol can augment the beneficial outcome of a lower dose of fenofibrate and reduces its toxic or side effects.
Publish Date 2016-03-04 19:53
Citation Abd El-Haleim EA, Bahgat AK, Saleh S. Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression. World J Gastroenterol 2016; 22(10): 2931-2948
URL http://www.wjgnet.com/1007-9327/full/v22/i10/2931.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i10.2931
Full Article (PDF) WJG-22-2931.pdf
Full Article (Word) WJG-22-2931.doc
Manuscript File 20549-Review.doc
Answering Reviewers 20549-Answering reviewers.pdf
Audio Core Tip 20549-Audio core tip.mp3
Biostatistics Review Certificate 20549-Biostatistics Statement.pdf
Conflict-of-Interest Disclosure Form 20549-Conflict of interest statement.pdf
Copyright License Agreement 20549-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 20549-Institutional animal care and use committe statement.pdf
Institutional Review Board Approval Form or Document 20549-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 20549-Language certificate.pdf
Peer-review Report 20549-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 20549-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 20549-Scientific misconduct check.pdf
Scientific Editor Work List 20549-Scientific editor work list.pdf