Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	20838
Country	United States

Received	2015-06-24 09:18
Peer-Review Started	2015-06-24 10:56
To Make the First Decision	2015-07-28 10:50
Return for Revision	2015-08-03 16:47
Revised	2015-09-09 11:30
Second Decision	2015-11-02 14:33
Accepted by Journal Editor-in-Chief	2015-11-05 23:15
Accepted by Company Editor-in-Chief	2015-11-17 09:17
Articles in Press	2015-11-17 09:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-19 20:24
Publish the Manuscript Online	2016-01-29 11:06

ISSN	2150-5349 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatitis C virus: A time for decisions. Who should be treated and when?
Manuscript Source	Invited Manuscript
All Author List	Bashar M Attar and David H Van Thiel
Funding Agency and Grant Number
Corresponding Author	Bashar M Attar, MD, PhD, MPH, Cook County Health and Hospitals System, Rush University Medical Center, 1901 West Harrison Street, Chicago, IL 60612, United States. battar@rush.edu
Key Words	Hepatitis C virus; Direct acting antivirals; Cirrhosis of the liver; Timing of treatment
Core Tip	This study presents the burden of hepatitis C virus (HCV) infection. Current guidelines limit treatment to those with advanced liver disease (Metavir F-3 or F-4 fibrosis). This represents a small fraction of those infected having the worse prognosis. They are unlikely to infect others. In contrast, the much larger group F-0 to F-2 is the vectors for additional infections. The plague of HCV can only be eliminated if the larger groups that infect others are treated. The cost of treating this larger population is expensive but much less expensive than treating only those with advanced fibrosis in the long run.
Publish Date	2016-01-29 11:06
Citation	Attar BM, Van Thiel DH. Hepatitis C virus: A time for decisions. Who should be treated and when? World J Gastrointest Pharmacol Ther 2016; 7(1): 33-40
URL	http://www.wjgnet.com/2150-5349/full/v7/i1/33.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i1.33

Full Article (PDF)	WJGPT-7-33.pdf
Full Article (Word)	WJGPT-7-33.doc
Manuscript File	20838-Review.docx
Answering Reviewers	20838-Answering reviewers.pdf
Audio Core Tip	20838-Audio core tip.m4a
Biostatistics Review Certificate	Biostatistics_Statement_20150623221027.docx
Clinical Trial Registration Statement	DeclarationOf_HelsinkiConformation_Statement_20150623220731.docx
Conflict-of-Interest Disclosure Form	20838-Conflict-of-interest statement.pdf
Copyright License Agreement	20838-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150623220251.docx
Institutional Review Board Approval Form or Document	Institutional_Review_Board_Statement_20150623215857.docx
Supplementary Material	Supplementary_Material_20150623215535.pdf
Peer-review Report	20838-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20838-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20838-Scientific misconduct check.pdf
Scientific Editor Work List	20838-Scientific editor work list.pdf