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2/22/2016 3:38:00 PM | Browse: 855 | Download: 1413
Publication Name World Journal of Hepatology
Manuscript ID 20991
Country/Territory Brazil
Received
2015-06-27 19:45
Peer-Review Started
2015-06-30 08:43
To Make the First Decision
2015-09-28 11:27
Return for Revision
2015-10-06 12:41
Revised
2015-11-05 06:01
Second Decision
2016-01-12 16:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-01-22 15:50
Articles in Press
2016-01-22 15:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-02-19 10:28
Publish the Manuscript Online
2016-02-22 15:38
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Burn injury induces histopathological changes and cell proliferation in liver of rats
Manuscript Source Invited Manuscript
All Author List Jeferson André Bortolin, Hananiah Tardivo Quintana, Tabata de Carvalho Tomé, Flavia Andressa Pidone Ribeiro, Daniel Araki Ribeiro and Flavia de Oliveira
Funding Agency and Grant Number
Funding Agency Grant Number
São Paulo Research Foundation, FAPESP 11/22034-9
Corresponding Author Flavia de Oliveira, PhD, Department of Biosciences, Federal University of São Paulo (UNIFESP), Rua Silva Jardim, 136 - Lab 328, Vila Mathias CEP, Santos, SP 11060-001, Brazil. flavia.oliveira@unifesp.br
Key Words Burn injury; Morphology; Histophatology; Liver; Ciclooxigenase-2
Core Tip Severe burn injuries result in serious compli-cations that involve host response related to inflam-mation and multiple organ dysfunction. The goal of this study was to investigate the temporal effects of extensive experimental burn injury (BI) in rat liver through the histopathological and morphoquantitative aspects, immunoexpression of ciclooxigenase-2 (COX-2) and liver gene expression of tumor necrosis factor-α, inducible nitric oxide synthase and caspase-3. Our results revealed that BI induces histopathological changes, upregulation of COX-2 immunoexpression, and cell proliferation in liver of rats.
Publish Date 2016-02-22 15:38
Citation Bortolin JA, Quintana HT, Tomé TC, Ribeiro FAP, Ribeiro DA, de Oliveira F. Burn injury induces histopathological changes and cell proliferation in liver of rats. World J Hepatol 2016; 8(6): 322-330
URL http://www.wjgnet.com/1948-5182/full/v8/i6/322.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i6.322
Full Article (PDF) WJH-8-322.pdf
Full Article (Word) WJH-8-322.doc
Manuscript File 20991-Review.doc
Answering Reviewers 20991-Answering reviewers.pdf
Audio Core Tip 20991-Audio core tip.wav
Biostatistics Review Certificate 20991-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 20991-Conflict-of-interest statement.pdf
Copyright License Agreement 20991-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 20991-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 20991-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 20991-Institutional review board statement.pdf
Peer-review Report 20991-Peer-review(s).pdf
Scientific Misconduct Check 20991-Scientific misconduct check.pdf
Scientific Editor Work List 20991-Scientific editor work list.pdf