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1/31/2016 4:11:00 PM | Browse: 1132 | Download: 1397
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 21139
Country/Territory United States
Received
2015-06-30 13:03
Peer-Review Started
2015-07-02 22:11
To Make the First Decision
2015-07-27 15:54
Return for Revision
2015-08-04 14:58
Revised
2015-09-23 00:00
Second Decision
2015-11-02 14:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-11-11 18:08
Articles in Press
2015-11-11 18:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-01-21 21:35
Publish the Manuscript Online
2016-01-31 16:11
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Alcoholic pancreatitis: New insights into the pathogenesis and treatment
Manuscript Source Invited Manuscript
All Author List Dahn L Clemens, Katrina J Schneider, Christopher K Arkfeld, Jaclyn R Grode, Mark A Wells and Shailender Singh
Funding Agency and Grant Number
Funding Agency Grant Number
University of Nebraska Department of Internal Medicine, the Fred and Pamela Buffett Cancer Center, and the Nebraska Research Initiative to Clemens DL
NIH to Arkfeld CK
NIAAA AA020818 (to Arkfeld CK)
Corresponding Author Dahn L Clemens, PhD, Associate Professor, Department of Internal Medicine, Section of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198-8098, United States. dclemens@unmc.edu
Key Words Alcohol; Pancreatitis; Alcoholic pancreatitis; Ethanol metabolism; Acute pancreatitis; Fatty acid ethyl esters
Core Tip There is currently no specific pharmacotherapy for pancreatitis. Although ethanol abuse is commonly associated with both acute and chronic pancreatitis, ethanol does not itself cause pancreatitis. Instead it appears that ethanol and its metabolic by-products sensitize the pancreas to damage from other factors. Detailed understanding of the mechanisms by which ethanol sensitizes the pancreas to damage has identified a number of promising targets for therapy. It is hoped that further preclinical and clinical studies will lead to the development of successful treatment of both acute and chronic pancreatitis.
Publish Date 2016-01-31 16:11
Citation Clemens DL, Schneider KJ, Arkfeld CK, Grode JR, Wells MA, Singh S. Alcoholic pancreatitis: New insights into the pathogenesis and treatment. World J Gastrointest Pathophysiol 2016; 7(1): 48-58
URL http://www.wjgnet.com/2150-5330/full/v7/i1/48.htm
DOI http://dx.doi.org/10.4291/wjgp.v7.i1.48
Full Article (PDF) WJGP-7-48.pdf
Full Article (Word) WJGP-7-48.doc
Manuscript File 21139-Review.docx
Answering Reviewers 21139-Answering reviewers.pdf
Audio Core Tip 21139-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 21139-Conflict-of-interest statement.pdf
Copyright License Agreement 21139-Copyright assignment.pdf
Peer-review Report 21139-Peer-review(s).pdf
Scientific Misconduct Check 21139-Scientific misconduct check.pdf
Scientific Editor Work List 21139-Scientific editor work list.pdf