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2/25/2016 7:04:00 PM | Browse: 1066 | Download: 2510
Publication Name World Journal of Gastroenterology
Manuscript ID 21375
Country China
Received
2015-07-09 09:28
Peer-Review Started
2015-07-09 10:55
To Make the First Decision
2015-09-29 14:29
Return for Revision
2015-09-30 09:52
Revised
2015-10-13 20:23
Second Decision
2015-11-09 16:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-11-24 17:22
Articles in Press
2015-11-24 17:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-12-29 03:52
Typeset the Manuscript
2016-01-14 16:54
Publish the Manuscript Online
2016-02-25 19:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Integrative & Complementary Medicine
Manuscript Type Basic Study
Article Title Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats
Manuscript Source Unsolicited Manuscript
All Author List Yang Zhang, Jian-Xing Luo, Xiao-Yu Hu, Fang Yang, Sen Zhong and Wu Lin
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Technology R and D Program 2008ZX10005
National Key Technology R and D Program 2009ZX10005
Corresponding Author Dr. Xiao-Yu Hu, Department of Infectious Diseases, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shierqiao Street, Chengdu 610072, Sichuan Province, China. xiaoyuhu@aliyun.com
Key Words Acute liver failure; Traditional Chinese medicine; Taohechengqi-tang; High mobility group box 1; Inflammation
Core Tip Acute liver failure (ALF) is a life-threatening condition. Our prospective cohort study demonstrated that high doses of herbs for clearing heat and resolving stasis have a protective effect on LF. However, the curative mechanism is unclear. Our evidence showed that improved prescription of Taohechengqi-tang attenuated the inflammatory reaction of ALF in rats via inhibition of high mobility group box 1 production, which may contribute to recovery of limited liver regeneration. We provide evidence for the clinical application of Chinese herbs for clearing heat and resolving stasis.
Publish Date 2016-02-25 19:03
Citation Zhang Y, Luo JX, Hu XY, Yang F, Zhong S, Lin W. Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats. World J Gastroenterol 2016; 22(8): 2558-2565
URL http://www.wjgnet.com/1007-9327/full/v22/i8/2558.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i8.2558
Full Article (PDF) WJG-22-2558.pdf
Full Article (Word) WJG-22-2558.doc
Manuscript File 21375-Review.doc
Answering Reviewers 21375-Answering reviewers.pdf
Audio Core Tip 21375-Audio core tip.mp3
Biostatistics Review Certificate 21375-Biostatistics statement.pdf
Clinical Trial Registration Statement DeclarationOf_HelsinkiConformation_Statement_20150708183522.docx
Conflict-of-Interest Disclosure Form 21375-Conflict-of-interest statement.pdf
Copyright License Agreement 21375-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20150708183244.doc
Institutional Animal Care and Use Committee Approval Form or Document 21375-Institutional animal care and use committee statement.docx
Institutional Review Board Approval Form or Document 21375-Institutional review board statement.docx
Non-Native Speakers of English Editing Certificate 21375-Language certificate.PDF
Peer-review Report 21375-Peer-review(s).pdf
Scientific Misconduct Check 21375-Scientific misconduct check.pdf
Scientific Editor Work List 21375-Scientific editor work list.pdf