Publication Name	World Journal of Orthopedics
Manuscript ID	21415
Country	Italy

Received	2015-07-10 08:20
Peer-Review Started	2015-07-24 19:44
To Make the First Decision	2015-09-16 09:14
Return for Revision	2015-09-22 18:11
Revised	2015-10-20 06:06
Second Decision	2015-11-27 15:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-08 15:19
Articles in Press	2015-12-08 15:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-26 19:01
Publish the Manuscript Online	2016-03-09 14:49

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Rheumatology
Manuscript Type	Review
Article Title	Major osteoporotic fragility fractures: Risk factor updates and societal impact
Manuscript Source	Invited Manuscript
All Author List	Paola Pisani, Maria Daniela Renna, Francesco Conversano, Ernesto Casciaro, Marco Di Paola, Eugenio Quarta, Maurizio Muratore and Sergio Casciaro
Funding Agency and Grant Number	Funding Agency Grant Number FESR P.O. Apulia Region 2007-2013 - Action 1.2.4 3Q5AX31
Corresponding Author	Sergio Casciaro, PhD, Eng, National Council of Research, Institute of Clinical Physiology, (CNR-IFC), c/o Campus Universitario Ecotekne, via per Monteroni, 73100 Lecce, Italy. sergio.casciaro@cnr.it
Key Words	Fracture prevention; Fracture risk; Fragility fracture; Osteoporosis; Hip fracture
Core Tip	The osteoporosis burden is growing and 9 million fractures occur each year worldwide. Unfor-tunately, because of the underutilization of available preventive strategies, only a minority of women and men at high fracture risk are identified and successively referred for treatment. The aim of this review is to analyze the most important factors related to the enormous impact of osteoporotic fractures on population. Because early diagnosis is the key to reduce the impact of osteoporosis on healthcare system, attention must be focused on the identification of high fracture risk among osteoporotic patients.
Publish Date	2016-03-09 14:49
Citation	Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, Muratore M, Casciaro S. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World J Orthop 2016; 7(3): 171-181
URL	http://www.wjgnet.com/2218-5836/full/v7/i3/171.htm
DOI	http://dx.doi.org/10.5312/wjo.v7.i3.171

Full Article (PDF)	WJO-7-171.pdf
Full Article (Word)	WJO-7-171.doc
Manuscript File	21415-Review.doc
Answering Reviewers	21415-Answering reviewers.pdf
Audio Core Tip	21415-Audio core tip.wav
Conflict-of-Interest Disclosure Form	21415-Conflict-of-interest statement.pdf
Copyright License Agreement	21415-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	21415-Language certificate.pdf
Peer-review Report	21415-Peer-review(s) .pdf
Scientific Misconduct Check	21415-Scientific misconduct check.pdf
Scientific Editor Work List	21415-Scientific editor work list.pdf