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3/22/2016 10:41:00 AM | Browse: 932 | Download: 1388
Publication Name World Journal of Cardiology
Manuscript ID 21926
Country United States
Received
2015-08-05 08:58
Peer-Review Started
2015-08-06 11:30
To Make the First Decision
2015-09-16 13:57
Return for Revision
2015-09-21 18:50
Revised
2015-10-05 12:11
Second Decision
2015-11-30 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-12-11 16:43
Articles in Press
2015-12-11 16:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-08 20:17
Publish the Manuscript Online
2016-03-22 10:41
ISSN 1949-8462 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Lipoprotein abnormalities in South Asians and its association with cardiovascular disease: Current state and future directions
Manuscript Source Invited Manuscript
All Author List Ozlem Bilen, Ayeesha Kamal and Salim S Virani
Funding Agency and Grant Number
Funding Agency Grant Number
American Heart Association Beginning 14BGIA20460366
American Diabetes Association Clinical Science and Epidemiology award 1-14-CE-44
Baylor College of Medicine Center for Globalization Award
Corresponding Author Salim S Virani, MD, PhD, Department of Medicine, Baylor College of Medicine, Health Services Research and Development (152) Michael E, DeBakey Veterans Affairs Medical Center 2002 Holcombe Blvd., Houston, TX 77030, United States. virani@bcm.edu
Key Words Dyslipidemia; South Asians; Asian Indians; Cardiovascular disease
Core Tip South Asians have a high prevalence of coro-nary heart disease (CHD) and suffer from early-onset CHD. Indeed, an important contributor is their unique lipid profile which is characterized by elevated levels of triglycerides, low levels of high-density lipoprotein (HDL) cholesterol, elevated lipoprotein(a) levels, a higher atherogenic particle burden despite comparable low-density lipoprotein cholesterol levels compared with other ethnic subgroups. HDL particles also appear to be smaller, dysfunctional, and proatherogenic. Despite the rapid expansion of the current literature with better understanding of the specific lipid abnormalities in this patient population, specific management goals and treatment thresholds do not exist for South Asians because of paucity of data. Current treatment recommendations are mostly extrapolated from Western guidelines. Lastly, large, prospective studies with outcomes data are needed to assess cardiovascular benefit associated with various lipid-lowering therapies (including combination therapy) in this patient population.
Publish Date 2016-03-22 10:41
Citation Bilen O, Kamal A, Virani SS. Lipoprotein abnormalities in South Asians and its association with cardiovascular disease: Current state and future directions. World J Cardiol 2016; 8(3): 247-257
URL http://www.wjgnet.com/1949-8462/full/v8/i3/247.htm
DOI http://dx.doi.org/10.4330/wjc.v8.i3.247
Full Article (PDF) WJC-8-247.pdf
Full Article (Word) WJC-8-247.doc
Manuscript File 21926-Review.doc
Answering Reviewers 21926-Answering reviewers.pdf
Audio Core Tip 21926-Audio core tip.wma
Conflict-of-Interest Disclosure Form 21926-Conflict-of-interest statement.pdf
Copyright License Agreement 21926-Copyright assignment.pdf
Peer-review Report 21926-Peer-review(s).pdf
Scientific Misconduct Check 21926-Scientific misconduct check.pdf
Scientific Editor Work List 21926-Scientific editor work list.pdf