| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparison of peg-interferon, ribavirin plus telaprevir vs simeprevir by propensity score matching
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hideki Fujii, Takeshi Nishimura, Atsushi Umemura, Taichiro Nishikawa, Kanji Yamaguchi, Michihisa Moriguchi, Yoshio Sumida, Hironori Mitsuyoshi, Chihiro Yokomizo, Saiyu Tanaka, Hiroki Ishikawa, Kenichi Nishioji, Hiroyuki Kimura, Shiro Takami, Yasuyuki Nagao, Takayuki Takeuchi, Toshihide Shima, Yoshihiko Sawa, Masahito Minami, Kohichiroh Yasui and Yoshito Itoh |
| Funding Agency and Grant Number |
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| Corresponding Author |
Hideki Fujii, MD, PhD, Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji Agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto 602-8566,
Japan. hidekifuiii710810@yahoo.co.jp
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| Key Words |
Chronic hepatitis C; Combination therapy; Pegylated interferon; Simeprevir; Telaprevir; Propensity score matching; Protease inhibitor |
| Core Tip |
We evaluated and compared the efficacy of telaprevir (TVR) and simeprevir (SMV) in combination with pegylated interferon and ribavirin in the treatment of chronic hepatitis C. patients in real-world clinical settings. In the TVR group, the proportion of patients achieving a virological response was higher than that in the SMV group according to the original data. After propensity score matching, the proportion of patients achieving a virological response during treatment and after 12 wk was almost identical between the two groups with no significant difference observed.
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| Publish Date |
2015-12-04 15:24 |
| Citation |
Fujii H, Nishimura T, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Sumida Y, Mitsuyoshi H, Yokomizo C, Tanaka S, Ishikawa H, Nishioji K, Kimura H, Takami S, Nagao Y, Takeuchi T, Shima T, Sawa Y, Minami M, Yasui K, Itoh Y. Comparison of peg-interferon, ribavirin plus telaprevir vs simeprevir by propensity score matching. World J Hepatol 2015; 7(28): 2841-2848 |
| URL |
http://www.wjgnet.com/1948-5182/full/v7/i28/2841.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v7.i28.2841 |
