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9/12/2014 8:41:00 PM | Browse: 933 | Download: 719
Publication Name World Journal of Gastroenterology
Manuscript ID 2227
Country/Territory Saudi Arabia
Received
2013-02-07 20:47
Peer-Review Started
2013-02-10 20:45
To Make the First Decision
2013-04-03 09:08
Return for Revision
2013-04-09 20:18
Revised
2013-05-21 20:39
Second Decision
2013-06-18 14:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-06-19 00:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-08-23 10:49
Publish the Manuscript Online
2013-09-14 11:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Autobiography
Article Title Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats
Manuscript Source Invited Manuscript
All Author List Salim S Al-Rejaie, Hatem M Abuohashish, Maher M Al-Enazi, Abdullah H Al-Assaf, Mihir Y Parmar and Mohammed M Ahmed
Funding Agency and Grant Number
Funding Agency Grant Number
Deanship of Scientific Research at King Saud University for its funding this research through the research group project RGP-VPP-266
Corresponding Author Salim S Al-Rejaie, Associate Professor of Pharmacology and Toxicology, Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, PO Box 55760, Riyadh 11544, Saudi Arabia. rejaie@ksu.edu.sa
Key Words Naringenin; Ulcerative colitis; Inflammatory bowel disease; Oxidative stress
Core Tip Inflammatory bowel disease (IBD), consisting of Crohn's disease (CD) and ulcerative colitis (UC), results in substantial morbidity and is difficult to treat. New strategies for adjunct therapies are needed. Systemic corticosteroids are highly effective at inducing clinical remission in cases of acute exacerbation of CD and UC; however, their use is limited by their frequent and sometimes severe side effects. Results of present study revealed that, naringenin has protective effects against acetic acid-induced UC by inhibiting inflammatory and oxidative bio-markers. Thus, it may pose promising outcomes for future clinical usage as a natural non-toxic effective supplement in IBD.
Publish Date 2013-09-14 11:17
Citation Al-Rejaie SS, Abuohashish HM, Al-Enazi MM, Al-Assaf AH, Parmar MY, Ahmed MM. Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats. World J Gastroenterol 2013; 19(34): 5633-5644
URL http://www.wjgnet.com/1007-9327/full/v19/i34/5633.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i34.5633
Full Article (PDF) WJG-19-5633.pdf
Manuscript File 2227-Review.docx
Answering Reviewers 2227-Answering reviewers.doc
Copyright License Agreement 2227-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 2227-Language certificate.pdf
Peer-review Report 2227-Peer review(s).pdf
Scientific Editor Work List 2227-Scientific editor work list.doc