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Articles Published Processes
5/2/2016 6:55:00 PM | Browse: 1071 | Download: 1146
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Received |
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2015-08-29 16:31 |
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Peer-Review Started |
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2015-09-06 20:22 |
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To Make the First Decision |
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2015-10-08 16:18 |
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Return for Revision |
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2015-10-19 00:50 |
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Revised |
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2015-10-30 22:02 |
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Second Decision |
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2016-01-27 13:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2016-02-16 09:48 |
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Articles in Press |
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2016-02-16 09:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-04-08 11:49 |
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Publish the Manuscript Online |
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2016-05-02 18:55 |
ISSN |
2219-2808 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Allergy |
Manuscript Type |
Review |
Article Title |
Fetal programming and early identification of newborns at high risk of free radical-mediated diseases
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Manuscript Source |
Invited Manuscript |
All Author List |
Serafina Perrone, Antonino Santacroce, Anna Picardi and Giuseppe Buonocore |
Funding Agency and Grant Number |
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Corresponding Author |
Serafina Perrone, MD, PhD, Department of Molecular and Developmental Medicine, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci 36, 53100 Siena, Italy. saraspv@yahoo.it
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Key Words |
Fetal programming; Oxidative stress; High-risk newborn; Biomarkers; Perinatal medicine; Metabolic syndrome |
Core Tip |
The adverse outcomes on the offspring born from altered gestation are already known. The consequences of these perturbations have been demonstrated even after many decades from birth. In this review we summarize gestational conditions associated to fetal programming and elucidate the mechanisms involved in such kind of occurrence. We also describe to what extent oxidative stress (OS) is involved in a very wide spectrum of genetic, metabolic, and cellular responses, through the gene expression regulation, and cell growth modulation. By virtue of these properties, OS has been nominated as the lowest common denominator of adult disease programming.
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Publish Date |
2016-05-02 18:55 |
Citation |
Perrone S, Santacroce A, Picardi A, Buonocore G. Fetal programming and early identification of newborns at high risk of free radical-mediated diseases. World J Clin Pediatr 2016; 5(2): 172-181 |
URL |
http://www.wjgnet.com/2219-2808/full/v5/i2/172.htm |
DOI |
http://dx.doi.org/10.5409/wjcp.v5.i2.172 |
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