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5/2/2016 6:55:00 PM | Browse: 1071 | Download: 1146
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 22461
Country/Territory Italy
Received
2015-08-29 16:31
Peer-Review Started
2015-09-06 20:22
To Make the First Decision
2015-10-08 16:18
Return for Revision
2015-10-19 00:50
Revised
2015-10-30 22:02
Second Decision
2016-01-27 13:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-02-16 09:48
Articles in Press
2016-02-16 09:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-04-08 11:49
Publish the Manuscript Online
2016-05-02 18:55
ISSN 2219-2808 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Allergy
Manuscript Type Review
Article Title Fetal programming and early identification of newborns at high risk of free radical-mediated diseases
Manuscript Source Invited Manuscript
All Author List Serafina Perrone, Antonino Santacroce, Anna Picardi and Giuseppe Buonocore
Funding Agency and Grant Number
Corresponding Author Serafina Perrone, MD, PhD, Department of Molecular and Developmental Medicine, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci 36, 53100 Siena, Italy. saraspv@yahoo.it
Key Words Fetal programming; Oxidative stress; High-risk newborn; Biomarkers; Perinatal medicine; Metabolic syndrome
Core Tip The adverse outcomes on the offspring born from altered gestation are already known. The consequences of these perturbations have been demonstrated even after many decades from birth. In this review we summarize gestational conditions associated to fetal programming and elucidate the mechanisms involved in such kind of occurrence. We also describe to what extent oxidative stress (OS) is involved in a very wide spectrum of genetic, metabolic, and cellular responses, through the gene expression regulation, and cell growth modulation. By virtue of these properties, OS has been nominated as the lowest common denominator of adult disease programming.
Publish Date 2016-05-02 18:55
Citation Perrone S, Santacroce A, Picardi A, Buonocore G. Fetal programming and early identification of newborns at high risk of free radical-mediated diseases. World J Clin Pediatr 2016; 5(2): 172-181
URL http://www.wjgnet.com/2219-2808/full/v5/i2/172.htm
DOI http://dx.doi.org/10.5409/wjcp.v5.i2.172
Full Article (PDF) WJCP-5-172.pdf
Full Article (Word) WJCP-5-172.doc
Manuscript File 22461-Review.docx
Answering Reviewers 22461-Answering reviewers.pdf
Audio Core Tip 22461-Audio core tip.aif
Conflict-of-Interest Disclosure Form 22461-Conflict-of-interest statement.pdf
Copyright License Agreement 22461-Copyright assignement.pdf
Non-Native Speakers of English Editing Certificate 22461-Language certificate.pdf
Peer-review Report 22461-Peer-review(s).pdf
Scientific Misconduct Check 22461-Scientific misconduct check.pdf
Scientific Editor Work List 22461-Scientific editor work list.pdf