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3/1/2016 2:39:00 PM | Browse: 1066 | Download: 1170
Publication Name World Journal of Nephrology
Manuscript ID 23051
Country/Territory United States
Received
2015-10-16 08:19
Peer-Review Started
2015-10-18 21:26
To Make the First Decision
2015-11-06 10:53
Return for Revision
2015-11-11 17:41
Revised
2015-11-20 00:50
Second Decision
2015-12-18 11:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-01-04 16:41
Articles in Press
2016-01-04 16:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-02-18 09:44
Publish the Manuscript Online
2016-03-01 14:46
ISSN 2220-6124 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms
Manuscript Source Invited Manuscript
All Author List Jeffrey H William and John Danziger
Funding Agency and Grant Number
Corresponding Author Jeffrey H William, MD, Division of Nephrology, Beth Israel Deaconess Medical Center and Harvard Medical School, 171 Pilgrim Road, Libby 2, Boston, MA 02215, United States. jhwillia@bidmc.harvard.edu
Key Words Hypomagnesemia; Proton-pump inhibitor; Magnesium; Nephrology; Renal
Core Tip Proton-pump inhibitor (PPI)-induced hypomagnesemia has become a well-recognized phenomenon over the past decade, through the publications of case reports and larger observational studies in the inpatient and outpatient populations. However, there are no prospective, controlled studies to support causation. Molecular mechanisms of magnesium transporters, including the pH-dependent regulation of transient receptor potential melastatin-6 transporters in the colonic enterocyte, have been proposed to explain the effect of PPIs on magnesium reabsorption, but may only comprise a small part of a more complicated interplay of molecular biology, pharmacology, and genetic predisposition.
Publish Date 2016-03-01 14:46
Citation William JH, Danziger J. Proton-pump inhibitor-induced hypo¬magnesemia: Current research and proposed mechanisms. World J Nephrol 2016; 5(2): 152-157
URL http://www.wjgnet.com/2220-6124/full/v5/i2/152.htm
DOI http://dx.doi.org/10.5527/wjn.v5.i2.152
Full Article (PDF) WJN-5-152.pdf
Full Article (Word) WJN-5-152.doc
Manuscript File 23051-Review.docx
Answering Reviewers 23051-Answering reviewers.pdf
Audio Core Tip 23051-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 23051-Conflict-of-interest statement.pdf
Copyright License Agreement 23051-Copyright assignment.pdf
Peer-review Report 23051-Peer-review(s).pdf
Scientific Misconduct Check 23051-Scientific misconduct check.pdf
Scientific Editor Work List 23051-Scientific editor work list.pdf