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3/28/2016 3:05:00 PM | Browse: 986 | Download: 1688
Publication Name World Journal of Gastroenterology
Manuscript ID 23199
Country/Territory China
Received
2015-11-24 08:26
Peer-Review Started
2015-11-25 09:02
To Make the First Decision
2015-12-11 10:17
Return for Revision
2015-12-11 15:57
Revised
2015-12-21 16:16
Second Decision
2015-12-29 07:59
Accepted by Journal Editor-in-Chief
2015-12-29 18:51
Accepted by Company Editor-in-Chief
2016-01-11 13:01
Articles in Press
2016-01-11 13:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-01-22 22:23
Typeset the Manuscript
2016-02-18 20:23
Publish the Manuscript Online
2016-03-28 15:05
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Apoptosis of human gastric carcinoma cells induced by Euphorbia esula latex
Manuscript Source Unsolicited Manuscript
All Author List Zhao-Ying Fu, Xiao-Dong Han, Ai-Hong Wang and Xiao-Bin Liu
Funding Agency and Grant Number
Funding Agency Grant Number
Shaanxi Provincial High-Level University Construction Project in Basic Medical Sciences 2013SXTS02
Yan’an Science and Technology Department 2014HM-05
Corresponding Author Dr. Zhao-Ying Fu, Professor, Institute of Molecular Biology and Immunology, Yan’an University, Yan’an 716000, Shaanxi Province, China. yadxfzy@yau.edu.cn
Key Words Euphorbia esula Linn; Apoptosis; Gastric carcinoma; Caspase; Bax; Bcl2
Core Tip Latex of Euphorbia esula (E. esula) is used to treat benign growths in traditional Chinese medicine. This led us to design an experiment to establish whether latex of E. esula can cause apoptosis. We found that E. esula extract inhibited proliferation and induced apoptosis in SGC-7901 cells, and that the action was caspase dependent and involved upregulation of Bax gene and downregulation of Bcl2 gene.
Publish Date 2016-03-28 15:05
Citation Fu ZY, Han XD, Wang AH, Liu XB. Apoptosis of human gastric carcinoma cells induced by Euphorbia esula latex. World J Gastroenterol 2016; 22(13): 3564-3572
URL http://www.wjgnet.com/1007-9327/full/v22/i13/3564.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i13.3564
Full Article (PDF) WJG-22-3564.pdf
Full Article (Word) WJG-22-3564.doc
Manuscript File 23199-Review.doc
Answering Reviewers 23199-Answering reviewers.pdf
Audio Core Tip 23199-Audio core tip.mp3
Biostatistics Review Certificate 23199-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 23199-Conflict-of-interest statement.pdf
Copyright License Agreement 23199-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 23199-Grant application forms.pdf
Institutional Animal Care and Use Committee Approval Form or Document 23199-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 23199-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 23199-Language certificate.pdf
Peer-review Report 23199-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 23199-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 23199-Scientific misconduct check.pdf
Scientific Editor Work List 23199-Scientific editor work list.pdf