BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/30/2016 5:39:00 PM | Browse: 1112 | Download: 5329
 |
Received |
|
2015-12-04 09:01 |
|
Peer-Review Started |
|
2015-12-04 14:10 |
|
To Make the First Decision |
|
2016-02-18 16:55 |
|
Return for Revision |
|
2016-02-20 15:05 |
|
Revised |
|
2016-02-24 18:27 |
|
Second Decision |
|
2016-03-04 18:06 |
|
Accepted by Journal Editor-in-Chief |
|
2016-03-05 09:46 |
|
Accepted by Company Editor-in-Chief |
|
2016-03-14 09:38 |
|
Articles in Press |
|
2016-03-14 10:44 |
 |
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2016-04-14 07:57 |
|
Typeset the Manuscript |
|
2016-05-03 10:48 |
|
Publish the Manuscript Online |
|
2016-05-30 17:40 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Qian, Elsie Oppermann, Andreas Tran, Ulli Imlau, Kun Qian and Thomas Josef Vogl |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81071241 |
|
| Corresponding Author |
Thomas Josef Vogl, PhD, Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University, D-60590 Frankfurt am Main, Germany. t.vogl@em.uni-frankfurt.de |
| Key Words |
Hepatocellular carcinoma; Transarterial chemoembolization; Integrin inhibitor; Nanoparticles; Matrix metalloprotein 9; Vascular endothelial growth factor; ACI rats |
| Core Tip |
Our experimental study was designed to reduce tumor progression and recurrence through a combination of transarterial administration of GRGDSP (integrin-inhibitor) loaded nanoparticles plus transarterial chemoembolization (TACE) in an animal model of liver tumor. Our data showed that the combined biological and interventional treatment is a safe and effective therapy compared with TACE alone or TACE plus GRGDSP. The combined multimodal targeting therapies exhibit tremendous advantages over conventional interventional therapy alone. |
| Publish Date |
2016-05-30 17:40 |
| Citation |
Qian J, Oppermann E, Tran A, Imlau U, Qian K, Vogl TJ. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol 2016; 22(21): 5042-5049 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i21/5042.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i21.5042 |
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
