Publication Name	World Journal of Gastroenterology
Manuscript ID	2383
Country	Malaysia

Received	2013-02-19 10:55
Peer-Review Started	2013-02-19 20:33
To Make the First Decision	2013-03-18 15:28
Return for Revision	2013-03-19 10:14
Revised	2013-03-22 17:35
Second Decision	2013-04-09 20:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-10 07:54
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-04-26 03:07
Typeset the Manuscript	2013-05-30 15:18
Publish the Manuscript Online	2013-06-20 16:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Gastric precancerous lesions are associated with gene variants in Helicobacter pylori-susceptible ethnic Malays
Manuscript Source	Invited Manuscript
All Author List	Sathiya Maran, Yeong Yeh Lee, Shuhua Xu, Nur-Shafawati Rajab, Norhazrini Hasan, Syed Hassan Syed Abdul Aziz, Noorizan Abdul Majid and Bin Alwi Zilfalil
Funding Agency and Grant Number	Funding Agency Grant Number Fundamental Research Grant Scheme (FRGS) 203/PPSP/6171121 Universiti Sains Malaysia 1001/PPSP/812016 Universiti Sains Malaysia 1001/PPSP/8122022 National Science Foundation of China 30971577 National Science Foundation of China 31171218 Shanghai Rising-Star Program 11QA1407600 Science Foundation of the Chinese Academy of Sciences (CAS) KSCX2-EW-Q-1-11 Science Foundation of the Chinese Academy of Sciences (CAS) KSCX2-EW-R-01-05 Science Foundation of the Chinese Academy of Sciences (CAS) KSCX2-EW-J-15-05
Corresponding Author	Yeong Yeh Lee, MD, FRCP, FACP, Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kota Bahru, Malaysia. justnleeyy@gmail.com
Key Words	Gastric precancerous lesions; Gene polymorphisms; Genome-wide association; Helicobacter pylori; Malays
Core Tip	Gastric cancer and its precancerous lesions are exceptionally rare among ethnic Malays. Gene variants may be associated with precancerous lesions in Helicobacter pylori-susceptible Malays. Genome-wide association was performed to identify gene variants in Malays with a spectrum of gastric precancerous lesions. Results indicated that at different phases of the Correa cascade, different gene variants were manifest, but they followed a pattern of progression similar to their histological and clinical stages. It is possible that, in addition to histological staging, gene variant markers may serve to identify different phases of gastric cancer progression in the near future.
Publish Date	2013-06-20 16:34
Citation	Maran S, Lee YY, Xu S, Rajab NS, Hasan N, Syed Abdul Aziz SH, Majid NA, Zilfalil BA. Gastric precancerous lesions are associated with gene variants in Helicobacter pylori-susceptible ethnic Malays. World J Gastroenterol 2013; 19(23): 3615-3622
URL	http://www.wjgnet.com/1007-9327/full/v19/i23/3615.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i23.3615

Full Article (PDF)	WJG-19-3615.pdf
Manuscript File	2383-Review.docx
Answering Reviewers	2383-Answering reviewers.doc
Copyright License Agreement	2383-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethical approval.docx
Non-Native Speakers of English Editing Certificate	2383-Language certificate.doc
Peer-review Report	2383-Peer review(s).pdf
Scientific Editor Work List	2383-Scientific editor work list.doc