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Publication Name World Journal of Gastroenterology
Manuscript ID 2396
Country/Territory Japan
2013-02-19 16:49
Peer-Review Started
2013-02-20 14:07
To Make the First Decision
2013-03-11 15:10
Return for Revision
2013-03-17 17:49
Second Decision
2013-04-09 20:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-04-10 07:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-05-30 15:19
Publish the Manuscript Online
2013-06-20 16:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Autobiography
Article Title Diagnostic value of endothelial markers and HHV-8 staining in gastrointestinal Kaposi sarcoma and its difference in endoscopic tumor staging
Manuscript Source Invited Manuscript
All Author List Naoyoshi Nagata, Toru Igari, Takuro Shimbo, Katsunori Sekine, Junichi Akiyama, Yohei Hamada, Hirohisa Yazaki, Norio Ohmagari, Katsuji Teruya, Shinichi Oka and Naomi Uemura
Funding Agency and Grant Number
Funding Agency Grant Number
National Center for Global Health and Medicine 21-101
Corresponding Author Naoyoshi Nagata, MD, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, 162-8655, Tokyo, Japan. nnagata_ncgm@yahoo.co.jp
Key Words Gastrointestinal Kaposi's sarcoma; Hematoxylin and eosin; CD31; CD34; D2-40; Human herpesvirus-8
Core Tip Diagnosis of gastrointestinal Kaposi sarcoma (GI-KS) is important because treatment specifics depend on the extent of the disease. Endoscopic biopsy is a definitive diagnostic method for GI-KS, but its diagnostic accuracy has not been fully studied. In the current study, receiver operating characteristic area under the curve of hematoxylin and eosin (HE) staining, lymphatic and blood vessel endothelial cell markers, and HHV-8 was found to be high (> 0.80), and its accuracy tended to increase with endoscopic tumor staging. D2-40 will be useful for complementing HE staining in the diagnosis of GI-KS, especially in the upper GI tract and for polypoid appearance.
Publish Date 2013-06-20 16:34
Citation Nagata N, Igari T, Shimbo T, Sekine K, Akiyama J, Hamada Y, Yazaki H, Ohmagari N, Teruya K, Oka S, Uemura N. Diagnostic value of endothelial markers and HHV-8 staining in gastrointestinal Kaposi sarcoma and its difference in endoscopic tumor staging. World J Gastroenterol 2013; 19(23): 3608-3614
Url http://www.wjgnet.com/1007-9327/full/v19/i23/3608.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i23.3608
Full Article (PDF) WJG-19-3608.pdf
Manuscript File 2396-Review.docx
Answering Reviewers 2396-Answering reviewers.doc
Copyright License Agreement 2396-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 2396-Language certificate.pdf
Peer-review Report 2396-Peer review(s).pdf
Scientific Editor Work List 2396-Scientific editor work list.doc