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5/4/2016 10:08:00 AM | Browse: 1079 | Download: 1843
Publication Name World Journal of Gastroenterology
Manuscript ID 24250
Country/Territory China
Received
2016-01-14 09:51
Peer-Review Started
2016-01-16 18:00
To Make the First Decision
2016-02-18 16:55
Return for Revision
2016-02-20 15:53
Revised
2016-02-27 23:31
Second Decision
2016-03-11 09:36
Accepted by Journal Editor-in-Chief
2016-03-11 23:53
Accepted by Company Editor-in-Chief
2016-03-18 17:26
Articles in Press
2016-03-18 17:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-03-30 04:12
Typeset the Manuscript
2016-04-08 11:20
Publish the Manuscript Online
2016-05-04 10:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Peer-review started: February 25, 2016
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Expression of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Bo Hong, Yun Qian, Hong Zhang, Yi-Wen Sang, Lin-Fang Cheng, Qi Wang, Song Gao, Min Zheng and Hang-Ping Yao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81272679
National Natural Science Foundation of China 81470851
Zhejiang Provincial Natural Science Foundation of China LQ16H160005
Zhejiang Provincial Natural Science Foundation of China LY15H080002
Medical Science and Technology Project of Zhejiang Province 201337756
Educational Commission of Zhejiang Province of China Y201328079
Corresponding Author Dr. Hang-Ping Yao, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. yaohangping@zju.edu.cn
Key Words Hepatocellular carcinoma; Hepatitis B virus; Hepatitis B virus X; B7-H4; Immunohistochemistry
Core Tip Hepatitis B virus (HBV) is a major public health problem, and HBV-related hepatocellular carcinoma (HBV-HCC) has an extremely poor prognosis due to the lack of effective treatments. B7-H4 is a newly characterized member of the B7 superfamily that is actively involved in regulating the pathogenesis of tumors. However, the intrahepatic expression of B7-H4 in HBV-HCC patients has not been described. In this study, we found that the higher expression of HBx and B7-H4 was correlated with tumor progression of HBV-HCC. Therefore, B7-H4 may be involved in facilitating HBV-related hepatocarcinogenesis.
Publish Date 2016-05-04 10:08
Citation Hong B, Qian Y, Zhang H, Sang YW, Cheng LF, Wang Q, Gao S, Zheng M, Yao HP. Expression of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2016; 22(18): 4538-4546
URL http://www.wjgnet.com/1007-9327/full/v22/i18/4538.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i18.4538
Full Article (PDF) WJG-22-4538.pdf
Full Article (Word) WJG-22-4538.doc
Manuscript File 24250-Review.doc
Answering Reviewers 24250-Answering reviewers.pdf
Audio Core Tip 24250-Audio core tip.mp3
Biostatistics Review Certificate 24250-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24250-Conflict-of-interest statement.pdf
Copyright License Agreement 24250-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 24250-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 24250-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 24250-Language certificate.pdf
Peer-review Report 24250-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24250-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24250-Scientific misconduct check.pdf
Scientific Editor Work List 24250-Scientific editor work list.pdf