| Category |
Oncology |
| Manuscript Type |
Autobiography |
| Article Title |
Non-AIDS-related Kaposi's sarcoma: A single-institution experience
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Pasquale Rescigno, Rossella Di Trolio, Carlo Buonerba, Gaia De Fata, Piera Federico, Davide Bosso, Antonella Virtuoso, Michela Izzo, Tania Policastro, Luca Vaccaro, Gianfranco Cimmino, Francesco Perri, Elide Matano, Mario Delfino, Sabino De Placido, Giovannella Palmieri and Giuseppe Di Lorenzo |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Giuseppe Di Lorenzo, MD, PhD, Genitourinary Cancer Section and Rare-Cancer Center, Medical Oncology Division, University Federico II, Via S. Pansini 5, 80131 Napoli, Italy. giuseppedilorenzoncol@hotmail.com |
| Key Words |
Kaposi’s sarcoma; Human herpes virus 8; Paclitaxel; Pegylated liposomal doxorubicin; Vinblastine |
| Core Tip |
Non-acquired immunodeficiency syndrome (AIDS)-related Kaposi’s sarcoma (KS) is usually relatively benign, with an indolent disease course. It appears to be highly responsive to a wide variety of chemotherapy agents, including pegylated liposomal doxorubicin, vinca-alkaloids, etoposide and taxanes. However, factors predictive of progression-free survival are lacking. In our series of 32 patients with non-AIDS-related KS, we showed that presence of nodular lesions (vs macular lesions only) was associated with a 3-fold increased risk of progression. If confirmed by further studies, such a finding may be useful to improve the therapeutic strategy for this disease at the individual level. |
| Publish Date |
2013-05-20 09:37 |
| Citation |
Rescigno P, Di Trolio R, Buonerba C, De Fata G, Federico P, Bosso D, Virtuoso A, Izzo M, Policastro T, Vaccaro L, Cimmino G, Perri F, Matano E, Delfino M, De Placido S, Palmieri G, Di Lorenzo G. Non-AIDS-related Kaposis sarcoma: A single-institution experience. World J Clin Oncol 2013; 4(2): 52-57 |
| URL |
http://www.wjgnet.com/2218-4333/full/v4/i2/52.htm |
| DOI |
http://dx.doi.org/10.5306/wjco.v4.i2.52 |
