Publication Name	World Journal of Gastroenterology
Manuscript ID	24722
Country	China

Received	2016-02-02 10:26
Peer-Review Started	2016-02-02 10:44
To Make the First Decision	2016-03-07 08:32
Return for Revision	2016-03-08 16:26
Revised	2016-03-22 11:42
Second Decision	2016-03-30 16:42
Accepted by Journal Editor-in-Chief	2016-03-30 17:14
Accepted by Company Editor-in-Chief	2016-04-07 16:05
Articles in Press	2016-04-07 16:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-04-29 02:46
Typeset the Manuscript	2016-05-12 12:36
Publish the Manuscript Online	2016-05-30 17:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Blood neutrophil-lymphocyte ratio predicts survival after hepatectomy for hepatocellular carcinoma: A propensity score-based analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Hao-Jie Yang, Zhe Guo, Yu-Ting Yang, Jing-Hang Jiang, Ya-Peng Qi, Ji-Jia Li, Le-Qun Li and Bang-De Xiang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81260331 Key Laboratory for High-Incidence Tumor Prevention and Treatment, Ministry of Education GKE2015-ZZ05
Corresponding Author	Bang-De Xiang, Professor, Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, 71 Hedi Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. yhj894924067@163.com
Key Words	Blood neutrophil-to-lymphocyte ratio; Hepatocellular carcinoma; Liver resection; Prognosis; Postoperative change in neutrophil-to-lymphocyte ratio
Core Tip	We retrospectively analyzed a relatively large cohort of patients and used propensity score matching to balance out biases related to patient selection. Our results suggest that preoperative neutrophil-to-lymphocyte ratio (NLR) is a significant predictor of poor overall and disease-free survival. We further suggest that postoperative decrease in NLR is associated with poor survival, although only in patients with high preoperative NLR. Finally, we show that preoperative NLR ≥ 2.81 may be a good complementary indicator of poor overall survival when elevated alpha-fetoprotein levels provide no prognostic information.
Publish Date	2016-05-30 17:40
Citation	Yang HJ, Guo Z, Yang YT, Jiang JH, Qi YP, Li JJ, Li LQ, Xiang BD. Blood neutrophil-lymphocyte ratio predicts survival after hepatectomy for hepatocellular carcinoma: A propensity score-based analysis. World J Gastroenterol 2016; 22(21): 5088-5095
URL	http://www.wjgnet.com/1007-9327/full/v22/i21/5088.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i21.5088

Full Article (PDF)	WJG-22-5088.pdf
Full Article (Word)	WJG-22-5088.doc
Manuscript File	24722-Review.doc
Answering Reviewers	24722-Answering reviewers.pdf
Audio Core Tip	24722-Audio core tip.mp3
Biostatistics Review Certificate	24722-Biostatistics statement.pdf
Clinical Trial Registration Statement	24722-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	24722-Conflict-of-interest statement.pdf
Copyright License Agreement	24722-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	24722-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	24722-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document	24722-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	24722-Language certificate.pdf
Peer-review Report	24722-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	24722-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	24722-Scientific misconduct check.pdf
Scientific Editor Work List	24722-Scientific editor work list.pdf