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Articles Published Processes
6/21/2016 6:11:00 PM | Browse: 979 | Download: 1603
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Received |
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2016-02-16 09:33 |
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Peer-Review Started |
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2016-02-17 18:01 |
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To Make the First Decision |
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2016-03-31 09:51 |
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Return for Revision |
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2016-04-01 11:02 |
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Revised |
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2016-04-11 15:20 |
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Second Decision |
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2016-04-22 10:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2016-05-04 18:31 |
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Articles in Press |
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2016-05-04 18:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-05-10 10:55 |
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Publish the Manuscript Online |
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2016-06-21 18:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hiroshi Mihara, Nobuhiro Suzuki, Ammar Abdullkader Boudaka, Jibran Sualeh Muhammad, Makoto Tominaga, Yoshiaki Tabuchi and Toshiro Sugiyama |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Toyama and JSPS KAKENHI |
26870214 |
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| Corresponding Author |
Hiroshi Mihara, MD, PhD, Assistant Professor, Department of Gastroenterology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. m164-tym@umin.net |
| Key Words |
Transient receptor potential vanilloid 4; Stomach; Gastric emptying; ATP |
| Core Tip |
A mechano-sensitive ion channel, transient receptor potential vanilloid 4 (TRPV4), is expressed in gastric epithelium and contributes to ATP release and gastric emptying. These findings suggest that gastric distension stimulates TRPV4 on gastric epithelium and released ATP stimulates sub-epithelial nerve fibers or acts on visceral smooth muscles. TRPV4 might be a promising novel diagnostic and therapeutic target for functional gastric disorders. |
| Publish Date |
2016-06-21 18:11 |
| Citation |
Mihara H, Suzuki N, Boudaka AA, Muhammad JS, Tominaga M, Tabuchi Y, Sugiyama T. Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia. World J Gastroenterol 2016; 22(24): 5512-5519 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i24/5512.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i24.5512 |
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