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9/15/2014 8:55:00 PM | Browse: 1275 | Download: 1180
Publication Name World Journal of Gastroenterology
Manuscript ID 2558
Country/Territory New Zealand
Received
2013-02-28 16:57
Peer-Review Started
2013-03-01 11:57
To Make the First Decision
2013-03-18 15:40
Return for Revision
2013-03-20 08:33
Revised
2013-04-18 07:39
Second Decision
2013-05-09 13:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-10 10:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-06-25 19:26
Publish the Manuscript Online
2013-07-06 17:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Research & Experimental Medicine
Manuscript Type Review
Article Title Why interleukin-10 supplementation does not work in Crohn's disease patients
Manuscript Source Invited Manuscript
All Author List Gareth J Marlow, Dominique van Gent and Lynnette R Ferguson
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Business, Innovation and Employment
Dutch Digestive Foundation
Corresponding Author Lynnette R Ferguson, Professor, Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. l.ferguson@auckland.ac.nz
Key Words Inflammatory bowel disease; Crohn's disease; Interleukin-10; Recombinant human interleukin-10
Core Tip Inflammatory bowel disease (IBD) is a chronic condition with no known cure. This review addresses the current available treatments for IBD before discussing a potential new treatment strategy using the immunoregulatory cytokine interleukin-10 (IL-10). To date clinical trial results have been disappointing. We highlight the limitations of current IL-10 supplementation treatment and suggest how, with changes to IL-10 delivery and the correct choice of patient, IL-10 supplementation could become a viable treatment option.
Publish Date 2013-07-06 17:46
Citation Marlow GJ, van Gent D, Ferguson LR. Why interleukin-10 supplementation does not work in Crohn’s disease patients. World J Gastroenterol 2013; 19(25): 3931-3941
URL http://www.wjgnet.com/1007-9327/full/v19/i25/3931.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i25.3931
Full Article (PDF) WJG-19-3931.pdf
Manuscript File 2558-Review.docx
Answering Reviewers 2558-Answering reviewers.pdf
Copyright License Agreement 2558-Copyright assignment.pdf
Peer-review Report 2558-Peer reviews.pdf
Scientific Editor Work List 2558-Scientific editor work list.doc