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Articles Published Processes
9/30/2016 5:59:00 PM | Browse: 955 | Download: 971
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Received |
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2016-03-23 08:56 |
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Peer-Review Started |
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2016-03-23 14:27 |
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To Make the First Decision |
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2016-05-12 14:37 |
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Return for Revision |
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2016-05-12 15:35 |
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Revised |
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2016-07-04 00:00 |
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Second Decision |
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2016-07-18 08:58 |
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Accepted by Journal Editor-in-Chief |
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2016-07-18 18:47 |
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Accepted by Company Editor-in-Chief |
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2016-08-01 15:18 |
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Articles in Press |
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2016-08-01 15:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-08-14 06:47 |
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Typeset the Manuscript |
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2016-09-22 14:53 |
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Publish the Manuscript Online |
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2016-09-30 18:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Defining response to radiotherapy in rectal cancer using magnetic resonance imaging and histopathological scales
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammed RS Siddiqui, Jemma Bhoday, Nicholas J Battersby, Manish Chand, Nicholas P West, Al-Mutaz Abulafi, Paris P Tekkis and Gina Brown |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Royal Marsden Hospital United Kingdom National Institute for Health Research Biomedical Research Centre |
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| Yorkshire Cancer Research and Pathological Society of Great Britain and Ireland |
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| Corresponding Author |
Dr. Gina Brown, Consultant Radiologist, Professor, Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton SM2 5PT,
United Kingdom. gina.brown@rmh.nhs.uk
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| Key Words |
Tumour regression; mrTRG; Poor response; Neo-adjuvant therapy; Rectal cancer |
| Core Tip |
The degree of primary tumour regression following neo-adjuvant therapy identified on final histopathological specimens is a prognostic factor and response variation has allowed risk stratification, aiding in post-surgical treatment and follow-up decisions. To do this effectively, we need to have a common language for defining good and poor response. Definitions of response using histopathology scales are heterogenous with 19 different scales. There is one pre-operative magnetic resonance imaging (MRI) scale. Outcomes of recurrence and survival histopathology regression assessments should use Mandard 1, 2/Dworak 3, 4 for good response and Mandard 3, 4, 5/Dworak 0, 1, 2 for poor response. MRI indicates good and poor response by mrTRG1-3 and mrTRG4-5, respectively.
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| Publish Date |
2016-09-30 18:06 |
| Citation |
Siddiqui MRS, Bhoday J, Battersby NJ, Chand M, West NP, Abulafi AM, Tekkis PP, Brown G. Defining response to radiotherapy in rectal cancer using magnetic resonance imaging and histopathological scales. World J Gastroenterol 2016; 22(37): 8414-8434 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i37/8414.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i37.8414 |
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