Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	25949
Country	United States

Received	2016-03-26 16:50
Peer-Review Started	2016-03-27 13:04
To Make the First Decision	2016-05-17 12:17
Return for Revision	2016-05-18 11:10
Revised	2016-06-01 14:09
Second Decision	2016-06-13 16:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-06-29 09:56
Articles in Press	2016-06-29 09:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-19 18:20
Publish the Manuscript Online	2016-08-23 15:21

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Topic Highlights
Article Title	Endoscopic applications of cryospray ablation therapy-from Barrett’s esophagus and beyond
Manuscript Source	Invited Manuscript
All Author List	Jayaprakash Sreenarasimhaiah
Funding Agency and Grant Number
Corresponding Author	Jayaprakash Sreenarasimhaiah, MD, Department of Internal Medicine, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, MC 9083, Dallas, TX 75390, United States. jayaprakash.sree@yahoo.com
Key Words	Barrett’s esophagus; Dysplasia; Esophageal carcinoma; Endoscopic cryoablation; Cryotherapy
Core Tip	The current standard of care in treatment of dysplastic Barrett’s esophagus is endoscopic ablation. Cryospray ablation, the newest modality can achieve complete eradication of dysplasia and intestinal meta-plasia in over 90% of patients. Unlike other endos-copic methods, its unique mechanisms and depth of injury enable successful ablation of early esophageal carcinoma, palliative debulking of advanced carcinoma and reduction of tumor ingrowth into stents. The appli-cations of cryospray ablation beyond the esophagus include control of bleeding from gastric antral vascular ectasia, portal hypertensive gastropathy, and radiation proctitis. This modality continues to evolve as an impor-tant tool of therapeutic endoscopy.
Publish Date	2016-08-23 15:21
Citation	Sreenarasimhaiah J. Endoscopic applications of cryospray ablation therapy-from Barrett’s esophagus and beyond. World J Gastrointest Endosc 2016; 8(16): 546-552
URL	http://www.wjgnet.com/1948-5190/full/v8/i16/546.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i16.546

Full Article (PDF)	WJGE-8-546.pdf
Full Article (Word)	WJGE-8-546.doc
Manuscript File	25949-Review.docx
Answering Reviewers	25949-Answering reviewers.pdf
Audio Core Tip	25949-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	25949-Conflict-of-interest statement.pdf
Copyright License Agreement	25949-Copyright assignment.pdf
Peer-review Report	25949-Peer-review(s).pdf
Scientific Misconduct Check	25949-Scientific misconduct check.pdf
Scientific Editor Work List	25949-Scientific editor work list.pdf