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9/4/2016 2:49:00 PM | Browse: 1055 | Download: 1714
Publication Name World Journal of Gastroenterology
Manuscript ID 26184
Country Denmark
Received
2016-03-30 10:11
Peer-Review Started
2016-04-05 09:29
To Make the First Decision
2016-05-30 09:21
Return for Revision
2016-05-30 14:10
Revised
2016-06-27 22:03
Second Decision
2016-07-21 18:37
Accepted by Journal Editor-in-Chief
2016-07-21 22:31
Accepted by Company Editor-in-Chief
2016-08-01 15:52
Articles in Press
2016-08-01 15:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-08-24 21:56
Publish the Manuscript Online
2016-09-04 14:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Prospective Study
Article Title Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life
Manuscript Source Invited Manuscript
All Author List Belinda K Mössner, Benjamin Staugaard, Janne Jensen, Søren Thue Lillevang, Peer B Christensen and Dorte Kinggaard Holm
Funding Agency and Grant Number
Funding Agency Grant Number
an unrestricted grant from Abbvie, Denmark
Corresponding Author Peer B Christensen, PhD, Associate Professor, Department of Infectious Diseases, Odense University Hospital, Sdr. Boulevard 29, DK 5000 Odense C, Denmark. peer.christensen@dadlnet.dk
Key Words Dried blood spot; Real-life; Screening; Hepatitis B; Hepatitis C; Human immunodeficiency virus; People who inject drugs; Drug-users; Prisoners
Core Tip This study shows that it is feasible to combine serology and nucleic acid screening for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections in one dried blood sample (DBS) collected in real life and analyzed using a modern laboratory platform. We observed a sensitivity and specificity of > 96% for HBV, HCV, and HIV and correctly classified 95% of all HCV patients into past vs chronic infections compared to simultaneously collected venous blood samples. The study confirms that DBSs are feasible samples in outreach clinics and confirms the high sensitivity and specificity of previous laboratory-based studies.
Publish Date 2016-09-04 14:49
Citation Mössner BK, Staugaard B, Jensen J, Lillevang ST, Christensen PB, Holm DK. Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life. World J Gastroenterol 2016; 22(33): 7604-7612
URL http://www.wjgnet.com/1007-9327/full/v22/i33/7604.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i33.7604
Full Article (PDF) WJG-22-7604.pdf
Full Article (Word) WJG-22-7604.doc
Manuscript File 26184-Review.docx
Answering Reviewers 26184-Answering reviewers.pdf
Audio Core Tip 26184-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 26184-Conflict-of-interest statement.pdf
Copyright License Agreement 26184-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 26184-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 26184-Language certificate.pdf
Peer-review Report 26184-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 26184-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 26184-Scientific misconduct check.pdf
Scientific Editor Work List 26184-Scientific editor work list.pdf