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9/4/2016 2:49:00 PM | Browse: 642 | Download: 945
Publication Name World Journal of Gastroenterology
Manuscript ID 27059
Country/Territory Poland
2016-05-08 13:32
Peer-Review Started
2016-05-08 20:24
To Make the First Decision
2016-06-20 10:52
Return for Revision
2016-06-28 09:20
2016-06-29 20:53
Second Decision
2016-07-07 10:07
Accepted by Journal Editor-in-Chief
2016-07-07 11:05
Accepted by Company Editor-in-Chief
2016-07-21 16:03
Articles in Press
2016-07-21 16:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-08-26 08:55
Publish the Manuscript Online
2016-09-04 14:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Basic Study
Article Title Impact of Helicobacter pylori on the healing process of the gastric barrier
Manuscript Source Invited Manuscript
All Author List Eliza Mnich, Magdalena Kowalewicz-Kulbat, Paulina Sicińska, Krzysztof Hinc, Michał Obuchowski, Adrian Gajewski, Anthony P Moran and Magdalena Chmiela
Funding Agency and Grant Number
Funding Agency Grant Number
National Science Centre of Poland DEC-2013/09/N/NZ6/00805
National Science Centre of Poland DEC-2015/17/N/NZ6/03490
Corresponding Author Magdalena Chmiela, Professor, PhD, Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland. chmiela@biol.uni.lodz.pl
Key Words Helicobacter pylori; Wound healing; Gastric barrier dysfunction
Core Tip This manuscript focused on the impact of Helicobacter pylori (H. pylori) antigens to the gastric mucosal barrier. We evaluated the effects of H. pylori antigens using in vitro two cellular models of gastric epithelial cells and fibroblasts, which had been independently exposed to H. pylori components. In this study, we showed different effects of subunit A of urease, cytotoxin associated gene A protein, lipopolysaccharide (LPS) as well as compounds included in a glycine acid extract on the regenerative activity of gastric epithelial cells and fibroblasts. Our results indicate deleterious, dose dependent influence of H. pylori LPS on this process.
Publish Date 2016-09-04 14:49
Citation Mnich E, Kowalewicz-Kulbat M, Sicińska P, Hinc K, Obuchowski M, Gajewski A, Moran AP, Chmiela M. Impact of Helicobacter pylori on the healing process of the gastric barrier. World J Gastroenterol 2016; 22(33): 7536-7558
URL http://www.wjgnet.com/1007-9327/full/v22/i33/7536.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i33.7536
Full Article (PDF) WJG-22-7536.pdf
Full Article (Word) WJG-22-7536.doc
Manuscript File 27059-Review.doc
Answering Reviewers 27059-Answering reviewers.pdf
Audio Core Tip 27059-Audio core tip.mp3
Biostatistics Review Certificate 27059-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 27059-Conflict-of-interest statement.pdf
Copyright License Agreement 27059-Copyright assignment.pdf
Data Sharing Statement 27059-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 27059-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 27059-Institutional animal care and use committe statement.pdf
Institutional Review Board Approval Form or Document 27059-Institutional review board statement.pdf
Peer-review Report 27059-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 27059-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 27059-Scientific misconduct check.pdf
Scientific Editor Work List 27059-Scientific editor work list.pdf