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Publication Name World Journal of Nephrology
Manuscript ID 2711
Country/Territory
Received
2013-03-11 08:33
Peer-Review Started
2013-03-12 11:54
To Make the First Decision
2013-03-26 11:30
Return for Revision
2013-04-01 10:43
Revised
2013-04-16 17:58
Second Decision
2013-05-18 17:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-20 00:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-05-28 14:34
Publish the Manuscript Online
2013-06-06 10:41
ISSN 2220-6124 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Brief Articles
Article Title Hepcidin-25 negatively predicts left ventricular mass index in chronic kidney disease patients
Manuscript Source
All Author List Yao-Peng Hsieh, Ching-Hui Huang, Chia-Ying Lee, Hung-Lin Chen, Ching-Yuang Lin and Chia-Chu Chang
Funding Agency and Grant Number
Corresponding Author Chia-Chu Chang, MD, Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, 135 Nanhsiao St., Changhua City 500, Taiwan. 27509@cch.org.tw
Key Words Hepcidin-25; Ferritin; Chronic kidney disease; Left ventricular mass; Left ventricular mass index
Core Tip Cardiovascular disease is the primary cause of death among chronic kidney disease (CKD) patients, and left ventricular hypertrophy is a powerful independent predictor of mortality for end-stage renal disease patients. Low left ventricular performance is associated with iron deficiency anemia in rats with CKD. Hepcidin-25, a recently discovered biologically active 25-amino acid peptide, plays a key role in the iron homeostasis. Chronic iron deficiency may, by itself, reduce exercise capacity and cause ultrastructural alterations in cardiomyocytes. In the study, we showed that patients in higher grade of CKD stage had the higher serum hepcidin levels, and that there was negative correlation between serum hepcidin level and LVMI.
Publish Date 2013-06-06 10:41
Citation Hsieh YP, Huang CH, Lee CY, Chen HL, Lin CY, Chang CC. Hepcidin-25 negatively predicts left ventricular mass index in chronic kidney disease patients. World J Nephrol 2013; 2(2): 38-43
URL http://www.wjgnet.com/2220-6124/full/v2/i2/38.htm
DOI http://dx.doi.org/10.5527/wjn.v2.i2.38
Full Article (PDF) WJN-2-38.pdf
Manuscript File 2711-Review.doc
Answering Reviewers 2711-Answering reviewers.doc
Copyright License Agreement 2711-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 2711-Language certificate.pdf
Peer-review Report 2711-Peer review(s).pdf
Scientific Editor Work List 2711-Scientific editor work list.doc