Publication Name	World Journal of Cardiology
Manuscript ID	27794
Country	Portugal

Received	2016-06-16 08:42
Peer-Review Started	2016-06-17 16:27
To Make the First Decision	2016-07-04 15:34
Return for Revision	2016-07-07 17:25
Revised	2016-07-14 00:47
Second Decision	2016-08-11 10:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-08-18 11:28
Articles in Press	2016-08-18 11:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-10-25 13:09
Publish the Manuscript Online	2016-10-26 15:44

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Physical activity in primary and secondary prevention of cardiovascular disease: Overview updated
Manuscript Source	Invited Manuscript
All Author List	Alberto J Alves, João L Viana, Suiane L Cavalcante, Nórton L Oliveira, José A Duarte, Jorge Mota, José Oliveira and Fernando Ribeiro
Funding Agency and Grant Number
Corresponding Author	Alberto J Alves, PhD, Research Center in Sports Sciences, Health and Human Development, CIDESD, University Institute of Maia, Av. Carlos Oliveira Campos - Castelo da Maia, 4475-690 Maia, Portugal. ajalves@ismai.pt
Key Words	Physical activity; Primary prevention; Secondary prevention; Cardiovascular disease; Health care evaluation mechanisms
Core Tip	This review describes the benefits of physical activity in primary and secondary prevention of cardio-vascular disease. Physical inactivity is related to high blood cholesterol and accumulation of visceral fat, accompanied by low-grade vascular inflammation, which in turn is associated with insulin resistance and atherosclerosis leading to the development of coronary artery disease. In contrast, physical activity decreases vascular inflammation, and improves endothelial function and coronary circulation, preventing myocardial ischemia. Health professionals and policy makers in public health should align strategies to increase participation in physical activity.
Publish Date	2016-10-26 15:44
Citation	Alves AJ, Viana JL, Cavalcante SL, Oliveira NL, Duarte JA, Mota J, Oliveira J, Ribeiro F. Physical activity in primary and secondary prevention of cardiovascular disease: Overview updated. World J Cardiol 2016; 8(10): 575-583
URL	http://www.wjgnet.com/1949-8462/full/v8/i10/575.htm
DOI	http://dx.doi.org/10.4330/wjc.v8.i10.575

Full Article (PDF)	WJC-8-575.pdf
Full Article (Word)	WJC-8-575.doc
Manuscript File	27794-Review.docx
Answering Reviewers	27794-Answering reviewers.pdf
Audio Core Tip	27794-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	27794-Conflict-of-interest statement.pdf
Copyright License Agreement	27794-Copyright assignment.pdf
Peer-review Report	27794-Peer review(s).pdf
Scientific Misconduct Check	27794-Scientific misconduct check.pdf
Scientific Editor Work List	27794-Scientific editor work list.pdf